Pertumbuhan dan Perkembangan Otak Fetus Mencit Setelah Induksi Ochratoxin A Selama Periode Organogenesis (Peer Review)

Setiawan, Arum and Sagi, Mammed and Asmara, Widya and Istriyati, Istriyati (2013) Pertumbuhan dan Perkembangan Otak Fetus Mencit Setelah Induksi Ochratoxin A Selama Periode Organogenesis (Peer Review). Jurusan Biologi FMIPA Universitas Cendrawasih.

[thumbnail of 1.52. PEER REVIEW  Pertumbuhan dan Perkembangan Otak Fetus Mencit Setelah Induksi Ochratoxin A.pdf]
Preview
Text
1.52. PEER REVIEW Pertumbuhan dan Perkembangan Otak Fetus Mencit Setelah Induksi Ochratoxin A.pdf

Download (783kB) | Preview

Abstract

This experiment was performed to examine the effects of Ochratoxin A (OTA) during organogenesis period on fetuses brain growth and development. Thirty pregnant mice were divided randomly into 5 groups of 6. Ochratoxin A was dissolved in sodium bicarbonate and administered orally on seventh to fourteenth days of gestation at dosage of 0.5, 1.0, 1.5 mg/kg bw, respectively. The remaining animals were used as an untreated control, and placebo were given by Sodium Bicarbonate. At the age of 18-day pregnancy, mice were sacrified dan taken its brains. The fetuses brain growth and development were observed by measure brain weight, cereberum width and length, cerebellum width and length,and the wall thichkness of cerebrum. Result of this studies indicated that OTA caused decreased of brain weight, the length and width of cerebrum and cerebellum, the wall thickness of cerebrum significantly.

Item Type: Other
Additional Information: Peer Review
Subjects:
Divisions: 08-Faculty of Mathematics and Natural Science > 46201-Biology (S1)
Depositing User: Dr Arum Setiawan
Date Deposited: 15 Feb 2021 07:38
Last Modified: 15 Feb 2021 07:38
URI: http://repository.unsri.ac.id/id/eprint/42459

Actions (login required)

View Item View Item