Preparation and Characterization of Ethosomes Loading Petai Pods Extract(Parkia speciosa Hassk.)

Fitrya, Fitrya (2021) Preparation and Characterization of Ethosomes Loading Petai Pods Extract(Parkia speciosa Hassk.). Science and Technology Indonesia, 6 (1). pp. 18-24. ISSN e-ISSN:2580-4391 p-ISSN:2580-4405

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Abstract

Abstract Preparation of petai pods extract (Parkia speciosa) into ethosome aim to increased penetration through the skin. The method of cold is used in preparing petai pods extract encapsulation by ethosome with variation in concentration of soya lecithin, propylene glycol, and ethanol. The proportion of optimum formula ethosome consisted were 0.2 g soya lecithin, 1 ml propylene glycol, and 4 ml ethanol that response values obtained pH of 4.74, viscosity of 0,950 cP, %EE of 74.326%, and stability of 7.288%. The resulted of optimum formula obtained were PDI of 0.23, zeta potential of -7.5 mV, and particle size of 818.7 nm. Ethosome showed spheric particle using Transmissin Electron Microscopy. The di usion analysis showed highest on ethosome of petai pods extract (9.525%) than petai pods extract (5.466%). The interaction study used FTIR show no chemical interaction extract pods and ethosome components.

Item Type: Article
Subjects: R Medicine > RS Pharmacy and materia medica > RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
Divisions: 08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User: M.Si, Apt. Fitrya Fitrya
Date Deposited: 17 Jun 2021 02:40
Last Modified: 17 Jun 2021 02:40
URI: http://repository.unsri.ac.id/id/eprint/48069

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