Peer Review: Activity Tests of Bioactive Material of Salung Leaf (Psychotria viridiflora Reinw. Ex. Blume) against Salmonella thypi Bacteria In Vitro And In Vivo

Salni, Salni (2021) Peer Review: Activity Tests of Bioactive Material of Salung Leaf (Psychotria viridiflora Reinw. Ex. Blume) against Salmonella thypi Bacteria In Vitro And In Vivo. Fakultas MIPA, Universitas Sriwijaya. (Unpublished)

[thumbnail of 3 Peer review JIFI.pdf]
Preview
Text
3 Peer review JIFI.pdf - Published Version

Download (1MB) | Preview

Abstract

Activity test of bioactive material of Salung leaf (Psychotria viridiflora Reinw. ex. Blume) against Salmonella thypi in vitro and in d out. Bioactive material was obtained from the maceration and followed by fr quid fractionation. Antibacterial activity test performed in vitro to determine the um inhibitory concentration (MIC) and in vivo to determine the ability of bioa in rats (Rattus norvegicus) infected by Salmonella typhi. Treatment of bioactive 10, 50 and 100 mg kg-1 of weight. The results showed that the MIC of salung l l to Salmonella typhi was 250 µg mL-1. Bioactive ingredient at dose of 10 and 50 ecrease the number of bacterial colonies to 4.14x106 cfu g-1 and 5.4x105 cfu g-1, fu g-1 as control. Bioactive material in weight of 100 mg kg-1 of weight could r f Salmonella typhi to zero after 12 days of treatment. The ability to reduce the a ies of the bioactive material 100 mg kg-1 of weight is equal to the ability of positive control chloramphenicol 10 mg kg-1 of weight.

Item Type: Other
Subjects:
Divisions: 08-Faculty of Mathematics and Natural Science > 46201-Biology (S1)
Depositing User: Salni Salni
Date Deposited: 28 Sep 2021 06:42
Last Modified: 28 Sep 2021 06:42
URI: http://repository.unsri.ac.id/id/eprint/50228

Actions (login required)

View Item View Item