Parisa, Nita and Kamaluddin, Muhammad Totong and Salni, Salni Peer review, Aphrodisiac Effects of Areca Fruit in Erectile Dysfunction Rat Model. Fakultas Kedokteran Universitas Sriwijaya,.
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Abstract
Background Erectile Dysfunction (ED) cases are quite high in both women and men and increase with age. Areca fruit, ginseng and purwoceng are plants that have been traditionally used to increase male vitality. Objective To analyze the efficacy of areca fruit, ginseng and purwoceng in sexual activity and hormonal level in erectile dysfunction rat model. Methods This is in vivo experimental research study with pre and post-test control group design located in the laboratory of animal house and the biomolecular laboratory Faculty of Medicine Sriwijaya University. The subjects of this study were albino rats (Rattus norvegicus), Wistar strains, divided into 6 groups are negative control, Sildenafil, Areca Fruit Extract (AFE) 50 mg/kgBW, AFE 100 mg/kgBW, Combination of Areca Fruit, Ginseng and Purwoceng (AGP) 50 mg/kgBW and AGP 100 mg/kgBW. Female rat was injected by giving 500 mg/100 g of subcutaneous progesterone and 10 μg/100 g of BB benzoate 48 hours before mating so that female mice enter the esterus phase. Results It was found that Combination of Areca fruit, Ginseng and Purwoceng (AGP) group 50mg/kgBW significantly improved testosterone levels compared to sildenafil, while single areca fruit (AFE) dose 50mg/kgBW increased FSH and LH levels as well as sildenafil statistically. Conclusion The combination of areca fruit, ginseng and purwoceng is effective as treatment for erectile dysfunction
| Item Type: | Other |
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| Subjects: | |
| Divisions: | 08-Faculty of Mathematics and Natural Science > 46201-Biology (S1) |
| Depositing User: | Salni Salni |
| Date Deposited: | 28 Sep 2021 09:59 |
| Last Modified: | 28 Sep 2021 09:59 |
| URI: | http://repository.unsri.ac.id/id/eprint/50367 |
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