PENGARUH PEMBERIAN PROBIOTIK Lactobacillus bulgaricus DAN MINYAK JAGUNG (Zea mays L.) TERHADAP JUMLAH SEL LEUKOSIT DAN SEL T CD4+ PADA TIKUS PUTIH

NURITASARI, ITA and Miksusanti, Miksusanti and Herlina, Herlina (2021) PENGARUH PEMBERIAN PROBIOTIK Lactobacillus bulgaricus DAN MINYAK JAGUNG (Zea mays L.) TERHADAP JUMLAH SEL LEUKOSIT DAN SEL T CD4+ PADA TIKUS PUTIH. Undergraduate thesis, Sriwijaya University.

	Text RAMA_48201_08061281722071.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (2MB) | Request a copy
	Text RAMA_48201_08061281722071_TURNITIN.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (7MB) | Request a copy
Preview	Text RAMA_48201_08061281722071_0023076802_0003077102_01_front_ref.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (1MB) | Preview
	Text RAMA_48201_08061281722071_0023076802_0003077102_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (204kB) | Request a copy
	Text RAMA_48201_08061281722071_0023076802_0003077102_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (329kB) | Request a copy
	Text RAMA_48201_08061281722071_0023076802_0003077102_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (940kB) | Request a copy
	Text RAMA_48201_08061281722071_0023076802_0003077102_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (53kB) | Request a copy
	Text RAMA_48201_08061281722071_0023076802_0003077102_06_ref.pdf - Bibliography Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (205kB) | Request a copy
	Text RAMA_48201_08061281722071_0023076802_0003077102_07_lamp.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (1MB) | Request a copy

Abstract

Lactobacillus bulgaricus is a lactic acid bacteria that can provide health benefits by improving the immune system on its host. Corn oil (Zea mays L.) has a relatively high content of linoleic acid (PUFA ω-6) and palmitic acid that can improve the immune system. This study aims to determine the effect of Lactobacillus bulgaricus probiotic administration with corn oil (Zea mays L.) on the body's immune system. The observed immunity parameters are the number of leukocyte cells, lymphocytes, neutrophils, monocytes, and CD4+ T cells. Test animals are grouped into 7 treatment groups, namely the normal group, P1 (probiotic suspension 0,75 mL/200gBW), P2 (corn oil 1 mL/200gBW), P3 (probiotic suspension 0,25 mL and corn oil 1 mL/200gBW), P4 (probiotic suspension 0,5 mL and corn oil 1 mL/200gBW), P5 (probiotic suspension 0,75 mL and corn oil 1 mL/200gBW), and P6 (probiotic suspension 1 mL and corn oil 1 mL/200gBW). Parametric statistical analysis method in the form of ANOVA with Tukey test (post hoc). The results showed a significant increase in the number of leukocyte, lymphocyte, neutrophil and T CD4+ cells (sig<0,05). Administration of probiotic suspension 0,5 mL with corn oil 1 mL/200gBW shows an increase in the number of leukocyte cells, lymphocytes, neutrophils and monocytes were highest with values of 34,40±2,10; 22,30±3,82; 8,07±3,99; and 3,57±0,71 (103 cells/μL) respectively. While the administration of probiotic suspension 1 mL with corn oil 1 mL/200gBW showed an increase in the number of CD4+ T cells at the highest of 9,33±1,53 cells / μL. Keywords: Lactobacillus bulgaricus, Corn Oil, Leukocyte Cell, CD4+ T Cell

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Lactobacillus bulgaricus, Minyak Jagung, Sel Leukosit, Sel T CD4+
Subjects:	Q Science > QP Physiology > QP(901)-(981) Experimental pharmacology Q Science > QR Microbiology > QR180 Immunology
Divisions:	08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User:	Ita Nuritasari
Date Deposited:	19 Nov 2021 03:43
Last Modified:	19 Nov 2021 03:43
URI:	http://repository.unsri.ac.id/id/eprint/57541

Actions (login required)

View Item