PERBANDINGAN ANTARA SKOR SOFA DAN MSOFA SEBAGAI PREDIKTOR MORTALITAS PASIEN KRITIS COVID-19

GULFISAPUTRA, MUHAMAD PRIMASRA and Haloho, Agustina Br. and Lestari, Mayang Indah (2021) PERBANDINGAN ANTARA SKOR SOFA DAN MSOFA SEBAGAI PREDIKTOR MORTALITAS PASIEN KRITIS COVID-19. Undergraduate thesis, Sriwijaya Univerisity.

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Abstract

Background: COVID-19 is an acute respiratory disease caused by a coronavirus of the Betacoronavirus genus, namely SARS-CoV-2. COVID-19 can cause various effects from asymptomatic to severe. The SOFA score is usually used to evaluate the degree of organ dysfunction in critically ill COVID-19 patients, but the SOFA score is expensive and invasive. Therefore, MSOFA was created which requires lower costs and is less invasive. The purpose of this study was to compare MSOFA and SOFA scores as predictors of mortality in critically ill COVID-19 patients in the ICU. Method: This type of research is analytic observational with secondary data collection and cross-sectional approach. The total sample that met the inclusion and exclusion criteria was 94 patients. Data is taken through medical records. Statistical analysis using chi square and ROC curves. Results: In this study, the results showed that the median age of the patient died was 58 years, the sex of the patient who died was male (34.3%), additional diagnosis of patients who died most were patients without surgical intervention (medical) (33.3%), the most comorbid in patients who died was hypertension (28 .2%), the median SOFA and MSOFA scores in patients who died were 7. Critically ill COVID-19 patients who had a SOFA score ≥5.5 had a 2.45 times greater risk of mortality (OR=2.448). Critically ill COVID-19 patients who have an MSOFA score ≥6.5 have a 2.9 times greater risk of mortality (OR=2,900). The SOFA score has a sensitivity of 69.1% and a specificity of 52.3% (Se 0.69; Sp 0.523; LR+ 1.448; LR-0.59), while the MSOFA score has a sensitivity of 60% and a specificity of 65.9%. (Se 0.600; Sp 0.659; LR+ 1.7; LR- 0.607. The SOFA score has an AUC of 0.602 (0.489-0.715) and the MSOFA score has an AUC of 0.607 (0.494-0.720). There is no significant comparison between SOFA and MSOFA scores. (p=0.068). Conclusion: The MSOFA score has the ability to predict mortality in critically ill COVID-19 patients in the ICU as well as the SOFA score.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Sequential Organ Failure Assessment (SOFA), COVID-19, ICU, Modified Sequential Organ Failure Assessment (MSOFA)
Subjects:	R Medicine > R Medicine (General) > R5-920 Medicine (General)
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Muhamad Primasra Gulfisaputra
Date Deposited:	03 Jan 2022 04:44
Last Modified:	03 Jan 2022 04:44
URI:	http://repository.unsri.ac.id/id/eprint/60585

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