ISOLASI SENYAWA METABOLIT SEKUNDER DARI EKSTRAK N-HEKSANA BATANG TUMBUHAN BROTOWALI (Tinospora crispa L) DAN UJI AKTIVITAS ANTIOKSIDANNYA

MASYITA, MASYITA and Muharni, Muharni and Elfita, Elfita (2014) ISOLASI SENYAWA METABOLIT SEKUNDER DARI EKSTRAK N-HEKSANA BATANG TUMBUHAN BROTOWALI (Tinospora crispa L) DAN UJI AKTIVITAS ANTIOKSIDANNYA. Undergraduate thesis, Sriwijaya University.

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Abstract

Isolation of secondary metabolite from n-hexane extract of the stem of Tinospora crispa had been done. The extraction was done by maceration. The extract of n-hexane was separated and purified by chromatography column techniques. Antioxidant activity of the isolated compound was conducted by DPPH (1.1-diphenylpycryl hidrazyl) method with concentration variation of 1000, 500, 250, 125, 62.5, 31.25, 15.625 and 7.8125 pg/mL. The isolated compound was a yellow oils. Based on spectroscopy data 1D-NMR and comparing with literature data which had been reported from endophityc fungi of brotowali stem, it was concluded that the isolated compound was bis-(2-ethylhexyl) phthalate with molecular formula C24O4H38. The antioxidant activity of the isolated compound showed IC50 232.9 pg/mL and was inactive as antioxidant.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Antioxidant, bis-(2-ethylhexyl) phthalate, Tinospora crispa
Subjects:	Q Science > QD Chemistry > QD146-197 Inorganic chemistry
Divisions:	08-Faculty of Mathematics and Natural Science > 47201-Chemistry (S1)
Depositing User:	Mrs Furika Furika
Date Deposited:	20 May 2022 07:09
Last Modified:	20 May 2022 07:09
URI:	http://repository.unsri.ac.id/id/eprint/70165

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