OPTIMASI SEDIAAN SUNSCREEN SPRAY GEL EKSTRAK ETANOL BIJI ALPUKAT (PERSEA AMERICANA MILL.) DAN ZINK OKSIDA DENGAN VARIASI HPMC - KARBOPOL 940

MARDIAH, AINUL and Shiyan, Shaum and Apriani, Elsa Fitria (2022) OPTIMASI SEDIAAN SUNSCREEN SPRAY GEL EKSTRAK ETANOL BIJI ALPUKAT (PERSEA AMERICANA MILL.) DAN ZINK OKSIDA DENGAN VARIASI HPMC - KARBOPOL 940. Undergraduate thesis, Sriwijaya University.

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Abstract

Excessive sun exposure can hurt the skin. Preparation of sunscreen spray gel is done to protect the skin from exposure to ultraviolet rays. This study aims to determine the physical properties of the optimum formula and the SPF value of the combined ethanol extract of avocado seeds and zinc oxide. In this study, there were 4 formulas produced by the Design Expert 12® program with the factorial design method and determined the response of drying power, adhesive dispersion, and viscosity. The optimum formula of spray gel of avocado seed ethanol extract and zinc oxide obtained was tested for drying power, adhesive dispersion test, viscosity, and centrifugation. The optimum formula for spray gel preparation of avocado seed ethanol extract and zinc oxide at a concentration of 0.26% HPMC and 0.13% carbopol 940. The drying power yield was 210±11.79 seconds, adhesive dispersion 26.83±1.85 seconds, viscosity 220±0.20 cPs. The results of centrifugation showed no phase separation. The SPF value of the avocado seed ethanol extract and zinc oxide sunscreen spray gel of avocado seed ethanol extract was obtained at 14.52 ± 0.01. Based on the study results, it can be concluded that the optimum formula for the spray gel preparation of avocado seed ethanol extract has activity as a sunscreen which is included in the medium protection is 14.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Ekstrak Etanol Biji Alpukat, zink oksida, HPMC, karbopol 940, SPF
Subjects:	R Medicine > RS Pharmacy and materia medica > RS192-199 Pharmaceutical technology
Divisions:	08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User:	Ainul Mardiah
Date Deposited:	15 Aug 2022 02:19
Last Modified:	15 Aug 2022 02:19
URI:	http://repository.unsri.ac.id/id/eprint/77193

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