IDENTIFIKASI GEN SHV-1PABA PENDERITA INFEKSI BAKTERI PRODUSEN EKTENDED SPECTRUM LACTAMASE (ESBL) DI RSUP DR. MOHAMMAD HOESIN PALEMBANG

RAHMA, RIZKY AMALIA and Yuwono, Yuwono and Ramdja, Muhaimin (2013) IDENTIFIKASI GEN SHV-1PABA PENDERITA INFEKSI BAKTERI PRODUSEN EKTENDED SPECTRUM LACTAMASE (ESBL) DI RSUP DR. MOHAMMAD HOESIN PALEMBANG. Undergraduate thesis, Sriwijaya University.

	Text RAMA_11201_04091001098.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (53MB) | Request a copy
Preview	Text RAMA_11201_04091001098_0010107105_9990459650_01_front_ref.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (15MB) | Preview
	Text RAMA_11201_04091001098_0010107105_9990459650_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (14MB) | Request a copy
	Text RAMA_11201_04091001098_0010107105_9990459650_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (5MB) | Request a copy
	Text RAMA_11201_04091001098_0010107105_9990459650_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (7MB) | Request a copy
	Text RAMA_11201_04091001098_0010107105_9990459650_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (7MB) | Request a copy
	Text RAMA_11201_04091001098_0010107105_9990459650_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (521kB) | Request a copy
	Text RAMA_11201_04091001098_0010107105_9990459650_06_ref.pdf - Bibliography Restricted to Repository staff only Available under License Creative Commons Attribution Share Alike. Download (3MB) | Request a copy
	Text RAMA_11201_04091001098_0010107105_9990459650_07_lamp.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (10MB) | Request a copy

Abstract

Resistensi bakteri produsen Extended Spectrum fi-Lactamase (ESBL) terhadap antibiotik golongan B-laktam seperti penisilin, sefalosporin generasi I, II, III dan aztreonam (kecuali cephamicin dan carbapenem) terus mengalami peningkatan dalam frekuensinya. Kemampuan galur ESBL menghidrolisis antibotik golongan B laktam secara luas disebabkan adanya sejumlah mutasi pada gen bakteri produsen ESBL. Salah satu jenis gen bakteri produsen ESBL yang paling sering ditemukan adalah SHV-1. Mengidentifikasi faktor genetik yang menyebabkan galur Extended Spectrumfi-Lactamase (ESBL) resisten pada penderita infeksi ESBL di RSUP. dr. Moh. Hoesin Palembang. Penelitian ini adalah penelitian observasional deskriptif dengan pendekatan survei klinis pada 78 penderita infeksi ESBL di RSUP. dr. Moh. Hoesin Palembang. Identifikasi galur ESBL dilakukan dengan double disk approximation test. Selanjutnya, uji konfirmasi untuk mendeteksi gen SHV-1 dilakukan dengan uji PCR, elektroforesis gel agarosa, dan visualisasi. Distribusi frekuensi gen SHV-1 pada penelitian ini adalah sebanyak 33 dari 78 sampel atau 42,31%. Salah satu faktor genetik yang menyebabkan galur Extended Spectrumfi Lactamase (ESBL) resisten pada penderita infeksi ESBL di RSUP. dr. Moh. Hoesin Palembang adalah gen SHV-1. Kata Kunci: resistensi, bakteri, antibiotik, ESBL, SHV-1

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	resistensi, bakteri, antibiotik, ESBL, SHV-1
Subjects:	R Medicine > RB Pathology > RB1-214 Pathology
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Mrs. Elly Suryani
Date Deposited:	14 Oct 2022 04:34
Last Modified:	14 Oct 2022 04:34
URI:	http://repository.unsri.ac.id/id/eprint/80681

Actions (login required)

View Item