POLA KEPEKAAN Klebsieila pneumoniae TERHADAP BEBERAPA ANTIMIKROBA DI RSMH PALEMBANG PERIODE JANUARI-DESEMBER 2012

PRATAMA, ADRIAN and Yuwono, Yuwono and Ghanie, Aisyah (2014) POLA KEPEKAAN Klebsieila pneumoniae TERHADAP BEBERAPA ANTIMIKROBA DI RSMH PALEMBANG PERIODE JANUARI-DESEMBER 2012. Undergraduate thesis, Sriwijaya University.

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Abstract

Introducrion: Klebsiella pneumoniae is an opportunistic pathogen that is more common in individuals with immunocompromised. Infections caused by these bacteria is often in urinary tract, respiratory tract, bloodstream, and soft tissue. Treatment of Klebsiella pneumoniae infections is very complicated since the emergence of beta-lactamase enzymes that cause resistance to multiple classes of antimicrobe.The purpose of this study was to know sensitivity pattems of Klebsiella pneumoniae to some antimicrobial drugs. Method: This research was a descriptive study using medical records in Clinical Microbiology Laboratory Dr. Mohammad Hoesin General Hospital Palembang from January until December 2012. Medical records used in the research were 999 Klebsiella pneumoniae isolats that had been done an antimicrobial susceptibility testing. The isolats were from 41 spesimen types, such as sputum (47%), urine (21%), pus (10,6%), blood (6,4%), and throat swabs (3,6%). Result: Klebsiella pneumoniae isolats were mostly sensitive to imipenem (96,3%), amikasin (90,2%), sulbactam (82,1%), and fosfomycin (81%). Otherwise, the most resisted antimicrobial drugs were cefpirome (74,7%), ampicillin-sulbactam (68,3%), cefazolin (66,7%), azitrhomycin (66,7%), cefipime (66,3%), and co-trimoxsazole (60,6%). Condusion: Klebsiella pneumoniae isolats were mostly sensitive to imipenem and resistant to cefpirome.

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: Klebsiella pneumoniae, antimicrobial drug, resistance, sensitivity.
Subjects: R Medicine > RC Internal medicine > RC705-779 Diseases of the respiratory system
Divisions: 04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User: Mrs Furika Furika
Date Deposited: 24 Nov 2022 05:58
Last Modified: 24 Nov 2022 05:58
URI: http://repository.unsri.ac.id/id/eprint/82484

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