KORELASI JUMLAH SEL CD4+ DAN CD8+ DENGAN ABSOLUTE LYMPHOCYTE COUNT (ALC) PADA PASIEN COVID-19 DI RSUP DR. MOHAMMAD HOESIN PALEMBANG

SAMOSIR, APRILIA PASKAH and Liana, Phey and Sari, Nurmalia Purnama (2022) KORELASI JUMLAH SEL CD4+ DAN CD8+ DENGAN ABSOLUTE LYMPHOCYTE COUNT (ALC) PADA PASIEN COVID-19 DI RSUP DR. MOHAMMAD HOESIN PALEMBANG. Undergraduate thesis, Sriwijaya University.

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Abstract

Background: Coronavirus Disease 2019 (COVID-19) is an infectious respiratory disease that spreads globally and was declared as a pandemic in March 2020. Laboratory examinations need to be carried out on patients infected with COVID-19 to establish a diagnosis. On laboratory examination, abnormal results were found, namely lymphopenia. Such results are often associated with significant changes in T cell counts, especially CD4+ T cells and CD8+ T cells. This study aims to analyze the correlation of CD4+ and CD8+ cell counts with absolute lymphocyte count (ALC) in COVID-19 patients. Method: The type of research used is analytical observational with a retrospective cohort approach. The sample in this study is medical record data of patients diagnosed with COVID-19 at RSUP Dr. Mohammad Hoesin Palembang from March 2022 to May 2022 which meets the inclusion and exclusion criteria. Sampling is carried out by total sampling. Results: In this study, there were 35 patients who met the inclusion and exclusion criteria. The results of this study showed that there was a strong significant correlation (p<0.05) between CD4+ cell count and absolute lymphocyte count (ALC) at MRS time (r=0.69, p=0.000). Then there was also a significant correlation (p<0.05) between CD8+ cell count and absolute lymphocyte count (ALC) at MRS time (r=0.543, p=0.001). Conclusion: There was a correlation of CD4+ and CD8+ cell counts with absolute lymphocyte count (ALC) in COVID-19 patients. Keywords: CD4+ lymphocytes, CD8+ lymphocytes, absolute lymphocyte count (ALC), Covid-19

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Limfosit CD4+, Limfosit CD8+, absolute lymphocyte count (ALC), Covid-19
Subjects:	R Medicine > R Medicine (General) > R5-920 Medicine (General)
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Aprilia Paskah Samosir
Date Deposited:	28 Dec 2022 08:25
Last Modified:	28 Dec 2022 08:25
URI:	http://repository.unsri.ac.id/id/eprint/84873

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