FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN OBAT KUMUR EKSTRAK ETANOL BUAH PINANG (ARECA CATECHU L.) TERHADAP BAKTERI STREPTOCOCCUS MUTANS SECARA IN VITRO

HANIYAH, ATIKAH and Untari, Budi and Wijaya, Dina Permata (2019) FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN OBAT KUMUR EKSTRAK ETANOL BUAH PINANG (ARECA CATECHU L.) TERHADAP BAKTERI STREPTOCOCCUS MUTANS SECARA IN VITRO. Undergraduate thesis, Sriwijaya University.

[img] Text
RAMA_48201_08061281520066.pdf - Accepted Version
Restricted to Repository staff only
Available under License Creative Commons Public Domain Dedication.

Download (2MB) | Request a copy
[img] Text
RAMA_48201_08061281520066_TURNITIN.pdf - Accepted Version
Restricted to Repository staff only
Available under License Creative Commons Public Domain Dedication.

Download (12MB) | Request a copy
[img]
Preview
Text
RAMA_48201_08061281520066_00102658002_NIDN2_01_front_ref_.pdf - Accepted Version
Available under License Creative Commons Public Domain Dedication.

Download (1MB) | Preview
[img] Text
RAMA_48201_08061281520066_00102658002_NIDN2_02.pdf - Accepted Version
Restricted to Repository staff only
Available under License Creative Commons Public Domain Dedication.

Download (291kB) | Request a copy
[img] Text
RAMA_48201_08061281520066_00102658002_NIDN2_03.pdf - Accepted Version
Restricted to Repository staff only
Available under License Creative Commons Public Domain Dedication.

Download (305kB) | Request a copy
[img] Text
RAMA_48201_08061281520066_00102658002_NIDN2_04.pdf - Accepted Version
Restricted to Repository staff only
Available under License Creative Commons Public Domain Dedication.

Download (452kB) | Request a copy
[img] Text
RAMA_48201_08061281520066_00102658002_NIDN2_05.pdf - Accepted Version
Restricted to Repository staff only
Available under License Creative Commons Public Domain Dedication.

Download (255kB) | Request a copy
[img] Text
RAMA_48201_08061281520066_00102658002_NIDN2_06_ref.pdf - Bibliography
Restricted to Repository staff only
Available under License Creative Commons Public Domain Dedication.

Download (347kB) | Request a copy
[img] Text
RAMA_48201_08061281520066_00102658002_NIDN2_07_lamp.pdf - Accepted Version
Restricted to Repository staff only
Available under License Creative Commons Public Domain Dedication.

Download (1MB) | Request a copy

Abstract

Areca extract (Areca catechu L.) was formulated into a mouthwash that aims to overcome caries. Areca nut (Areca catechu L.) contains tannin compounds that proanthocyanidin which can inhibit the enzymatic activity of glucosyltransferase from Streptoccus mutans. The ethanol extract of areca nut was formulated in three mouthwash formulas with variations in extract concentration of 1,25 %, 2,5 % and 5 %. Areca nut extracted by maceration using ethanol 96%. Mouthwashes was analyzed by using organoleptic, pH, specific gravity, stability and antibacterial activity. Antibacterial activity test employed agar diffusion method with paper disc divided into five groups, that was three mouthwash formulas with variations in extract concentration of 1,25 %, 2,5 % and 5 %, positive controls (minosep®) and negative control (formula without extract). The inhibition diameter zone measure was scaled by using ImageJ®. The higher concentration of extract with the increasing of antibacterial test against Streptoccus mutans. The results showed that the variations in the concentration of extracts affected organoleptic, pH, viscosity and specific gravity of the formulas. The inhibition zone was caused by the mouthwash with extract concentration of 1,25 % was 3,307 ± 0,887 mm, concentration of 2,5 % was 6,111 ± 0,290 mm and 5 % was 7,851 ± 1,272 mm.

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: karies, buah pinang, obat kumur, Streptococcus mutans
Subjects: R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User: Atikah Haniyah
Date Deposited: 10 Oct 2019 02:26
Last Modified: 10 Oct 2019 02:26
URI: http://repository.unsri.ac.id/id/eprint/11285

Actions (login required)

View Item View Item