FORMULASI DEODORAN LOTION DARI MINYAK ATSIRI SERAI DAPUR (Cymbopogon citratus) DAN UJI AKTIVITAS ANTIBAKTERI TERHADAP Staphylococcus epidermidis

NAZIHA, NAZIHA and Miksusanti, Miksusanti and Apriani, Elsa Fitria (2024) FORMULASI DEODORAN LOTION DARI MINYAK ATSIRI SERAI DAPUR (Cymbopogon citratus) DAN UJI AKTIVITAS ANTIBAKTERI TERHADAP Staphylococcus epidermidis. Undergraduate thesis, Sriwijaya University.

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Abstract

Body odor is a problem that disrupts daily life. Staphylococcus epidermidis is one of the cause of body odor. The citral content in lemongrass essential oil has the potential to act as an antibacterial, whereas deodorants in lotion form work directly on local tissue and the desired therapeutic effect is more easily achieved. This research aims to create deodorant lotion with various concentrations of lemongrass essential oil (1%, 3%, and 5%) as an antibacterial agent against S.epidermidis. Evaluation tests include organoleptic, pH, viscosity, spreadability, adhesion, irritation, and stability. Data analysis using SPSS revealed that the best formulation is Formula 3 with a 3% concentration. It has slightly thick liquid texture, white color, distinctive scent, homogeneity, pH of 6.20±0.31, viscosity of 7.298±0.198 cP, spreadability of 6.20±0.24 cm, adhesion of 7.02±0.71 seconds, non-irritating, and stable during storage. Antibacterial activity, assessed using the agar well diffusion method, resulted in a zone of inhibition diameter of 11.17±0.41 mm. The Minimum Inhibitory Concentration (MIC) for the deodorant lotion with lemongrass essential oil was 2500 ppm, while the control with pure lemongrass essential oil was 5000 ppm. The Minimum Bactericidal Concentration (MBC) for both the deodorant lotion and pure lemongrass essential oil was 10000 ppm. Formula 3 of the deodorant lotion has the best characterization and strong antibacterial activity against Staphylococcus epidermidis.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Deodorant lotion, Lemongrass essential oil,
Subjects:	R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions:	08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User:	Naziha Naziha
Date Deposited:	21 May 2024 01:09
Last Modified:	21 May 2024 01:09
URI:	http://repository.unsri.ac.id/id/eprint/144394

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