PENGARUH EKSTRAK AQUADES RIMPANG TEMU MANGGA (CURCUMA MANGGA VAL.) TERHADAP ANTIINFLAMASI MENCIT (MUS MUSCULUS) GALUR SWISS WEBSTER DAN SUMBANGANNYA DALAM PEMBELAJARAN BIOLOGI SMA

AL IHSANI, DIFA DAMARYAN and Tibrani, Masagus Muhammad (2025) PENGARUH EKSTRAK AQUADES RIMPANG TEMU MANGGA (CURCUMA MANGGA VAL.) TERHADAP ANTIINFLAMASI MENCIT (MUS MUSCULUS) GALUR SWISS WEBSTER DAN SUMBANGANNYA DALAM PEMBELAJARAN BIOLOGI SMA. Undergraduate thesis, Sriwijaya University.

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Abstract

This study aims to determine the effect of aqueous extract of Curcuma mangga Val. rhizome on the anti-inflammatory response in mice (Mus musculus). The study employs an experimental method with a completely randomized design (CRD) consisting of five treatment groups: a negative control (aqueous solution), a positive control (Sodium Diclofenac 0.13 mg/kgBW), and three doses of Curcuma mangga rhizome extract (7 mg/kgBW, 28 mg/kgBW, and 56 mg/kgBW). Each treatment was administered orally 15 minutes before induction with 1 % of egg white. The mice's edema volume was measured every hour for six hours after inflammation induction using egg white. Data were analyzed using One-Way ANOVA and Duncan's Multiple Range Test (DMRT). The One-Way ANOVA results indicated a significant effect of Curcuma mangga aqueous extract on the anti-inflammatory response, while the DMRT results showed that the 56 mg/kgBW dose had the most significant anti-inflammatory effect, with an edema inhibition percentage of 63%, closely approaching the effectiveness of Sodium Diclofenac at 62%. This study also contributes to high school biology education through a Student Worksheet (LKPD) related to the immune system topic.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Ekstrak aquades rimpang temu mangga, Antiinflamasi, Mencit, Putih telur 1%, LKPD
Subjects:	R Medicine > RM Therapeutics. Pharmacology > RM270-282 Immunotherapy. Serotherapy
Divisions:	06-Faculty of Education and Educational Science > 84205-Biology Education (S1)
Depositing User:	Difa Damaryan Al Ihsani
Date Deposited:	18 Mar 2025 04:41
Last Modified:	18 Mar 2025 04:41
URI:	http://repository.unsri.ac.id/id/eprint/169170

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