FORMULASI EKSTRAK DAUN GAMBIR (UNCARIA GAMBIR ROXB.) SEBAGAI KOSMETIK PEMBERSIH WAJAH (CLEANSING WATER)

MAWARNI, IKA and Shiyan, Shaum (2023) FORMULASI EKSTRAK DAUN GAMBIR (UNCARIA GAMBIR ROXB.) SEBAGAI KOSMETIK PEMBERSIH WAJAH (CLEANSING WATER). Undergraduate thesis, Sriwijaya University.

	Text RAMA_48201_08061181924010.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (2MB) | Request a copy
	Text RAMA_48201_08061181924010_TURNITIN.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (7MB) | Request a copy
	Text RAMA_48201_08061181924010_0028058601_01_front_ref.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (1MB)
	Text RAMA_48201_08061181924010_0028058601_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (191kB) | Request a copy
	Text RAMA_48201_08061181924010_0028058601_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (282kB) | Request a copy
	Text RAMA_48201_08061181924010_0028058601_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (496kB) | Request a copy
	Text RAMA_48201_08061181924010_0028058601_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (6kB) | Request a copy
	Text RAMA_48201_08061181924010_0028058601_06_ref.pdf - Bibliography Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (264kB) | Request a copy
	Text RAMA_48201_08061181924010_0028058601_07_lamp.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (1MB) | Request a copy

Abstract

Catechins are flavonoid compounds that contain antioxidants that can prevent cell damage from free radicals and reduce excess melanin production by inhibiting the tyrosinase enzyme. Delivery of active substances is more effective when done in dosage forms, so gambir extract is formulated into facial cleansers that can deliver active substances properly. This study aims to obtain an optimum formula and have good cleaning effectiveness with the addition of gambier extract, which contains catechins. Gambir ethyl acetate extract facial cleanser will be formulated using the Design-Expert® application with a factorial design method of 22, which produces 4 formulas with varying concentrations of Tween 80 and PEG-400. The responses observed in this study were % transmittance, globule size, PDI, zeta potensial and % net power. The total level of flavonoids produced from the ethyl acetate extract of Gambir leaves was 767.42 mg CE/g extract. The optimum formula uses tween 80 and PEG-400 concentrations of 18% and 8%, respectively. The optimum formula produces a transmittance of 98.93%, a globule size of 29.77 nm, a PDI of 0.519, a zeta potential of 5.91 mV, and a cleanability of 69.27%. The optimum organoleptic formula is yellow, clear, and has a distinctive aroma of gambir extract. There is no phase separation. The results of the characterization of the optimum formula showed a pH of 5.78 and a viscosity of 1.61 mPa.s and the organoleptic yield after the stability test showed no difference between the pre-test preparations and no phase separation. Based on the data, it can be concluded that the optimum formula has good globule characteristics, cleanability, and is physically stable.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Cleansing Water, Pembersih Wajah, Daun Gambir, Optimasi, Faktorial 22
Subjects:	R Medicine > RS Pharmacy and materia medica > RS125-131.9 Formularies. Collected prescriptions R Medicine > RS Pharmacy and materia medica > RS192-199 Pharmaceutical technology R Medicine > RS Pharmacy and materia medica > RS400-431 Pharmaceutical chemistry
Divisions:	08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User:	Ika Mawarni
Date Deposited:	25 May 2023 02:19
Last Modified:	25 May 2023 02:19
URI:	http://repository.unsri.ac.id/id/eprint/105032

Actions (login required)

View Item