UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN SURUHAN (Peperomia Pellucida L) TERHADAP Staphylococcus aureus SECARA IN VITRO

MAHARANI, NADYAH and Haksajiwo, Valentino (2023) UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN SURUHAN (Peperomia Pellucida L) TERHADAP Staphylococcus aureus SECARA IN VITRO. Undergraduate thesis, Sriwijaya University.

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Abstract

Introduction: Staphylococcus aureus is one of the opportunistic bacteria in the oral cavity that can cause various diseases, including periapical abscesses. The treatment of microbial infections needed to pay attention to selected antibiotics. Traditional medicine was very popular with the community because it had very minimal side effects and the availability that is easy to obtain. Suruhan leaves could be utilized as an antibacterial due to their content of tannins, saponins, flavonoids and alkaloids which inhibit bacterial growth. Purpose: This study aimed to determine the effectiveness of the antibacterial extract of suruhan leaves (Peperomia pellucida L) against Staphylococcus aureus. Methods: This study was an in vitro laboratory experimental study. The test group used an extract of suruhan leaf with concentrations of 20%, 40% and 60% obtained by the soxhlation method, clindamycin was used as a positive control and aquades as a negative control. The antibacterial potency was tested using the disc diffusion method to determine the value of the inhibition zone, the dilution method to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC). The inhibition zone values were then analyzed statistically using one-way ANOVA and Post-Hoc Tukey tests. Results: This study revealed that the 60% concentration of extract suruhan leaf had an average inhibition zone of 18.27 mm, but smaller than clindamycin. The MIC test results of extract suruhan leaf were determined at a concentration of 20% and MBC at 40%. Conclusion: Suruhan leaf extract (Peperomia pellucida L.) had antibacterial activity against Staphylococcus aureus. Keywords: antibacterial, suruhan leaves, Peperomia Pellucida L, Staphylococcus aureus

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Kata kunci: antibakteri, daun suruhan, Peperomia Pellucida L, Staphylococcus aureus
Subjects:	R Medicine > RK Dentistry > RK529-535 Oral surgery
Divisions:	04-Faculty of Medicine > 12201-Dentistry (S1)
Depositing User:	Users 30252 not found.
Date Deposited:	30 May 2023 05:16
Last Modified:	30 May 2023 05:16
URI:	http://repository.unsri.ac.id/id/eprint/105991

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