The Effect of Antibacterial Agent of Pangasius sutchi Bone Extract Against Porphyromonas gingivalis

PRATAMA, MUHAMMAD RIZKY and Dewi, Siti Rusdiana Puspa and Awalia, Hema (2023) The Effect of Antibacterial Agent of Pangasius sutchi Bone Extract Against Porphyromonas gingivalis. Sriwijaya Journal of Dentistry (SJD), 4 (1). pp. 11-18. ISSN 2746-0592

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Abstract

Introduction:Periodontal disease is the most common dental problem mainly due to bacterial infection. The highest virulence bacteria found in periodontal disease isPorphyromonas gingivalis.Pangasius sutchibone extract contains bioactive peptides which have the potential effect to inhibit the growth of Gram-negative bacteria such asP.gingivalis.Purpose:This study aimedto determine the effect of an antibacterial agentof Pangasius sutchi bone extract against Porphyromonas gingivalis.Methods:This research wasin vitrolaboratory experimental study with a post-test-only control group design. The treatment groups consisted of Pangasius sutchibone extract using concentrations of 10%, 20%, 40%, 60%, and 100%, positive control(cefixime)and negative control(placebo). Results:The results showed that each concentration ofPangasius sutchibone extract had antibacterial properties. The largest diameter of the inhibitory zone was at 100% concentration. The minimum Bactericidal Concentration (MBC) was at a concentration of 40%, and the Minimum Inhibitory Concentration (MIC) was 20%.Conclusion:Pangasius sutchibone extract had an antibacterial effect againstPorphyromonas gingivalis.

Item Type:	Article
Subjects:	R Medicine > RK Dentistry > RK1-715 Dentistry
Divisions:	04-Faculty of Medicine > 12201-Dentistry (S1)
Depositing User:	Siti Dewi
Date Deposited:	19 Dec 2023 03:05
Last Modified:	19 Dec 2023 03:05
URI:	http://repository.unsri.ac.id/id/eprint/134752

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