POLA SENSITIVITAS BAKTERI Pseudomonas aerginosa TERHADAP ANTIBIOTIK PADA PASIEN RAWAT INAP DI RSUP DR. MOHAMMAD HOESIN PALEMBANG PERIODE MEI 2022 – APRIL 2023

NINGTIYAS, SALWA ADILAH and Nawawi, Rizki Andini and Diba, Masayu Farah (2023) POLA SENSITIVITAS BAKTERI Pseudomonas aerginosa TERHADAP ANTIBIOTIK PADA PASIEN RAWAT INAP DI RSUP DR. MOHAMMAD HOESIN PALEMBANG PERIODE MEI 2022 – APRIL 2023. Undergraduate thesis, Sriwijaya University.

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Abstract

Background: Pseudomonas aeruginosa is a Gram-negative bacteria that causes opportunistic and healthcare-acquired infections. It is capable of rapidly developing antibiotic resistance during treatment. The resistance of P. aeruginosa to antibiotics will complicate the treatment and recovery of patients, as well as increase morbidity and mortality due to long hospitalization period, complicated treatment, and high medical costs. Method: Descriptive observational research with a cross-sectional study design using data from the Clinical Microbiology Laboratory and Medical Records Installation of RSUP Dr. Mohammad Hoesin Palembang period of May 2022 – April 2023. The data were analyzed univariately and presented in the form of tables, diagrams, and descriptive narratives. Results: Pseudomonas aeruginosa was found to infect 465 hospitalized patients. The mortality rate in hospitalized patients was 26,7%. Adult patients aged 18–65 years dominated as much as 71%. The majority of patients were male, 51,2%. Most examination specimens used sputum, as much as 40%. The most common clinical diagnoses were surgical wound infection, diabetic foot ulcer, and pneumonia. The majority of patients came from the non-ICU room, as much as 71%. Patients were often found to undergo hospitalization for 8–14 days, as much as 25,2%. The sensitivity test results showed the best results in amikacin, and the worst in cefazoline and tigecycline. Conclusion: The sensitivity pattern of Pseudomonas aeruginosa to antibiotics showed that the bacteria were most sensitive to amikacin (94,2%). The antibiotic resistance profile in patients found Probable-PDR 0,9%, XDR 6,7%, MDR 24,7%, and non-MDR 67,7%, and DTR 2,4% and non-DTR 97,6%. Keywords: Pseudomonas aeruginosa, Hospitalized patients, Antibiotic resistance

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Pseudomonas aeruginosa, Pasien rawat inap, Resistensi antibiotik
Subjects:	R Medicine > RC Internal medicine > RC109-216 Infectious and parasitic diseases
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Salwa Adilah Ningtiyas
Date Deposited:	29 Dec 2023 04:39
Last Modified:	29 Dec 2023 04:39
URI:	http://repository.unsri.ac.id/id/eprint/137168

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