HUBUNGAN JENIS PROFILAKSIS SEKUNDER TERHADAP KEJADIAN REKURENSI PASIEN DEMAM REMATIK AKUT DAN PENYAKIT JANTUNG REMATIK DI RSUP DR. MOHAMMAD HOESIN PALEMBANG

MAHARANI, SHAHNAS PUTRI and Yosy, Deny Salverra and Karmila, Ariesti (2023) HUBUNGAN JENIS PROFILAKSIS SEKUNDER TERHADAP KEJADIAN REKURENSI PASIEN DEMAM REMATIK AKUT DAN PENYAKIT JANTUNG REMATIK DI RSUP DR. MOHAMMAD HOESIN PALEMBANG. Undergraduate thesis, Sriwijaya University.

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Abstract

Background: Acute rheumatic fever is an advanced complication of tonsilopharynigitis caused by Group A Streptococus β haemolyticus (GAS) bacterial infection. If not treated properly, re-infection can occur that can cause progressive valvular heart damage which can eventually develop into rheumatic heart disease. The most effective way to prevent recurrent infection is by giving long-term antibiotics in the form of secondary prophylaxis. The objective of this study is to investigate the relationship between the type of secondary prophylaxis given with the incidence of recurrent attacks in patients with acute rheumatic fever and rheumatic heart disease at Dr Mohammad Hoesin Hospital Palembang. Method: This study used analytical observational method with cross-sectional study design. Samples were taken by means of total sampling determined and in accordance with the inclusion and exclusion criteria. The data taken were primary data in the form of telephone interviews and secondary data in the form of patient medical records. Results: Among the 92 samples, most patients with acute rheumatic fever and rheumatic heart disease were found to be female (53.3%), school-aged children (5-15 years old) (93.5%), diagnosed for 1-2 years (67.4%), residing outside Palembang City (63%), having moderate economic level (39.1%), having parents with high school education level both father (56.5%) and mother (70.7%), and having high occupancy density (57.6%). In bivariate analysis, there was a significant association between occupancy density (P = 0.008), compliance level (P < 0.001), and type of secondary prophylaxis (P = 0.038) with the incidence of recurrence, but there was no significant association between gender (P = 0, 951), address (P = 0.112), economic level (P = 0.948), parental education (P = 0.55 and P = 0.486) age at diagnosis (P = 0.876), and length of time diagnosed (P = 0.322) with recurrence. The results of multivariate analysis showed that the level of compliance was the most dominant factor causing the incidence of recurrence in this study with an OR value = 0.151 (95% CI 0.051-0.449) and an AOR value = 4.890 (95% CI 1.469-16.282). Conclusion: There is an association between the type of secondary prophylaxis and the incidence of recurrence in patients with acute rheumatic fever and rheumatic heart disease at Dr Mohammad Hoesin Hospital Palembang. Keywords: Acute Rheumatic Fever, Rheumatic Heart Disease, Recurrence, Secondary Prophylaxis

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Demam Rematik Akut, Penyakit Jantung Rematik, Rekurensi, Profilaksis Sekunder
Subjects:	R Medicine > RJ Pediatrics > RJ1-570 Pediatrics R Medicine > RJ Pediatrics > RJ370-550 Diseases of children and adolescents R Medicine > RJ Pediatrics > RJ52-53 Therapeutics R Medicine > RM Therapeutics. Pharmacology > RM1-950 Therapeutics. Pharmacology
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Shahnas Putri Maharani
Date Deposited:	08 Jan 2024 06:49
Last Modified:	08 Jan 2024 06:49
URI:	http://repository.unsri.ac.id/id/eprint/137674

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