EFEKTIVITAS ANTIBAKTERI EKSTRAK DAUN MIANA TERHADAP BAKTERI Porphyromonas gingivalis

NABILA, AMANDA PUTRI and Kawuryani, Budi Asri and Yasmin, Ulfa (2024) EFEKTIVITAS ANTIBAKTERI EKSTRAK DAUN MIANA TERHADAP BAKTERI Porphyromonas gingivalis. Undergraduate thesis, Sriwijaya University.

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Abstract

Introduction: Gingivitis is an inflammatory condition that involves the soft tissue around the teeth (gingiva). The main factor causing gingivitis in children and adolescents is the accumulation of bacterial deposits on the teeth and gingival sulcus. One of the bacteria that cause gingivitis is the bacterium Porphyromonas gingivalis. Chlorhexidine is commonly used as the gold standard for preventing gingivitis, but it can cause side effects such as brown discoloration of teeth, impaired taste, and irrtitaion of mucosa. Miana leaves are natural ingredients that are often used as alternative medicines due to their antibacterial effects because they contain flavonoids, tannins, alkaloids, saponins, and essential oils. This study aims to determine the antibacterial effectiveness of miana leaf extract against Porphyromonas gingivalis bacteria. Material & Methods: The study used miana leaves for laboratory experimental research. There were five treatment groups consisting of 20%, 40%, and 60% concentration of miana leaf extract. 0.2% chlorhexidine as a positive control, and aquadest as a negative control. The inhibition zone test was carried out using the disc diffusion method and the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) tests using the solid dilution method. Result: There was a significant difference between all treatment groups (p<0.05). The inhibition zone had the largest diameter of 16.16 mm at a 60% concentration, which was smaller than the 22.22 mm diameter of the 0.2% chlorhexidine. The MIC was obtained at 20% concentration and the MBC was obtained at 40% concentration. Conclusion: Miana leaf extract had an antibacterial effect against Porphyromonas gingivalis bacteria.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	antibacterial, miana leaves, Porphyromonas gingivalis
Subjects:	R Medicine > RK Dentistry > RK1-715 Dentistry
Divisions:	04-Faculty of Medicine > 12201-Dentistry (S1)
Depositing User:	Amanda Putri Nabila
Date Deposited:	01 Jul 2024 02:45
Last Modified:	01 Jul 2024 02:45
URI:	http://repository.unsri.ac.id/id/eprint/148539

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