UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN SIRIH MERAH (Piper crocatum) TERHADAP PERTUMBUHAN Aggregatibacter actinomycetemcomitans

DHARMAWAN, DEBBY DESLIANDRY and Negara, Mellani Cindera and Meiliyanawaty, Rina (2024) UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN SIRIH MERAH (Piper crocatum) TERHADAP PERTUMBUHAN Aggregatibacter actinomycetemcomitans. Undergraduate thesis, Sriwijaya University.

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Abstract

Latar belakang: Aggregatibacter actinomycetemcomitans adalah bakteri gram negatif yang paling sering ditemukan pada periodontitis. Daun sirih merah sebagai bahan alami dilaporkan memiliki kandungan senyawa berupa flavonoid, alkaloid, tanin, saponin dan minyak atsiri yang terbukti memiliki efek antibakteri. Tujuan: Mengetahui ada atau tidaknya aktivitas antibakteri ekstrak daun sirih merah (Piper crocatum) terhadap pertumbuhan Aggregatibacter actinomycetemcomitans. Metode: Penelitian eksperimental laboratoris secara in vitro dengan desain post-test only control group yang terdiri dari ekstrak daun sirih merah konsentrasi 25%, 50%, 75% dan kontrol negatif berupa akuades dengan pengulangan sebanyak 6 kali. Penentuan nilai KHM dilakukan dengan menggunakan metode dilusi cair dan nilai KBM ditentukan dengan metode dilusi padat. Data nilai KHM dan nilai KBM dianalisis menggunakan uji Chi-square. Hasil: Nilai KHM ekstrak daun sirih merah di tetapkan pada konsentrasi 25% dan nilai KBM ekstrak daun sirih merah di tetapkan pada konsentrasi 50%. Kesimpulan: Ekstrak daun sirih merah (Piper crocatum) memiliki pengaruh daya antibakteri terhadap pertumbuhan Aggregatibacter actinomycetemcomitans dengan nilai KHM di tetapkan pada konsentrasi 25% dan nilai KBM di tetapkan pada konsentrasi 50%.

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: Aggregatibacter actinomycetemcomitans, antibakteri, daun sirih merah
Subjects: R Medicine > RK Dentistry > RK1-715 Dentistry
R Medicine > RK Dentistry > RK280 Oral and dental anatomy and physiology
R Medicine > RK Dentistry > RK301-493 Oral and dental medicine. Pathology. Diseases
Divisions: 04-Faculty of Medicine > 12201-Dentistry (S1)
Depositing User: Debby Desliandry Dharmawan
Date Deposited: 22 Jul 2024 08:07
Last Modified: 22 Jul 2024 08:07
URI: http://repository.unsri.ac.id/id/eprint/152704

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