PROFIL KLINIS DAN LABORATORIUM PASIEN SEPSIS DI PEDIATRIC INTENSIVE CARE UNIT RUMAH SAKIT UMUM PUSAT DR. MOHAMMAD HOESIN PALEMBANG

KHAIRUNNISA, SANDRINA and Saputra, Indra and Karmila, Ariesti (2024) PROFIL KLINIS DAN LABORATORIUM PASIEN SEPSIS DI PEDIATRIC INTENSIVE CARE UNIT RUMAH SAKIT UMUM PUSAT DR. MOHAMMAD HOESIN PALEMBANG. Undergraduate thesis, Sriwijaya University.

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Abstract

Sepsis is still one of the leading causes of mortality in children, which is associated with immune immaturity. Early identification of sepsis based on region-specific clinical and laboratory characteristics is expected will be able to reduce mortality. This study was a retrospective descriptive study using a cross-sectional approach. The subjects were patients diagnosed with sepsis in the pediatric intensive care unit of Dr. Mohammad Hoesin Hospital Palembang in May 2022 to May 2024 who met the inclusion and exclusion criteria. This study showed that the prevalence of sepsis patients was 28,01%, dominated by males (50,6%), and the majority was in the infant age group (35,4%). Most patients came from outside Palembang City (74,7%), and most parents were entrepreneurs (69,9%). Normal nutritional was predominant (46,8%), and malignancy was the most common comorbidity (24,1%). The physical examination showed that most patients had decreased consciousness, as indicated by GCS <11 (65,8%). Laboratory results showed the majority of patients had leukocytosis (41,8%), high NLR (68,4%), anemia (77,2%), thrombocytopenia (57%), elevated CRP (84,8%), elevated procalcitonin (78%), and positive blood culture (94,7%). The dominant source of infection was from respiratory system (49,4%). The majority had respiratory organ dysfunction (28,9%). The length of treatment was predominantly <7 days (68,3%). The majority of patients died (83,5%), and invasive ventilation was used for more than 48 hours (46,85%). In shock sepsis, inotropes and vasopressors were used most (84,8%). Pediatric sepsis patients in the PICU are dominated by male gender and infant age group. The majority of patients had decreased consciousness with laboratory findings of anemia, thrombocytopenia, leukocytosis, and increased NLR, CRP, and procalcitonin. The primary source of infection and organ dysfunction was the respiratory system. The mortality rate is high.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Sepsis Anak, Klinis, Laboratorium, dan PICU
Subjects:	R Medicine > R Medicine (General) > R5-920 Medicine (General) R Medicine > R Medicine (General) > R735-854 Medical education. Medical schools. Research R Medicine > RJ Pediatrics > RJ1-570 Pediatrics
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Sandrina Khairunnisa
Date Deposited:	10 Jan 2025 08:07
Last Modified:	10 Jan 2025 08:07
URI:	http://repository.unsri.ac.id/id/eprint/163601

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