SUHARTO, FADEL FIKRI and Indrajaya, Taufik and Riviati, Nur (2024) HUBUNGAN KADAR HSCRP DENGAN ATEROSKLEROSIS PADA USIA LANJUT DI RSUP DR. MOHAMMAD HOESIN PALEMBANG. Masters thesis, Sriwijaya University.
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Abstract
Latar Belakang Aterosklerosis adalah penyebab utama morbiditas dan mortalitas pada usia lanjut. Penanda inflamasi high-sensitivity C-reactive protein (hsCRP) diketahui berperan penting dalam proses inflamasi vaskular yang memengaruhi progresivitas aterosklerosis. Penelitian ini bertujuan untuk mengevaluasi hubungan kadar hsCRP dengan aterosklerosis pada pasien lanjut usia di RSUP Dr. Mohammad Hoesin Palembang. Metode Penelitian ini menggunakan desain case-control dengan jumlah 100 sampel. Kadar hsCRP diukur menggunakan metode laboratorium standar, sedangkan aterosklerosis dinilai berdasarkan ketebalan intima-media arteri karotis (CIMT) menggunakan Doppler ultrasound. Data dikumpulkan dari pasien usia ≥60 tahun yang memenuhi kriteria inklusi. Hasil Dari hasil analisis, terdapat perbedaan bermakna kadar hsCRP antara kelompok dengan aterosklerosis (CIMT ≥1,5 mm) dibandingkan kelompok tanpa aterosklerosis. Kadar hsCRP yang lebih tinggi bermakna positif dengan kejadian aterosklerosis, dengan nilai prediksi optimal pada kadar hsCRP >2 mg/L. Simpulan Adanya hubungan signifikan antara kadar hsCRP dengan aterosklerosis pada pasien lanjut usia. hsCRP dapat menjadi penanda prognostik dalam memprediksi risiko aterosklerosis serta membantu pengembangan strategi intervensi preventif pada kelompok usia lanjut. Kata kunci: Aterosklerosis, hsCRP, usia lanjut, tunika intima arteri karotis
Item Type: | Thesis (Masters) |
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Uncontrolled Keywords: | Atherosclerosis, hsCRP, elderly, carotid intima-media thickness |
Subjects: | R Medicine > RC Internal medicine > RC31-1245 Internal medicine R Medicine > RC Internal medicine > RC666-701 Diseases of the circulatory (Cardiovascular) system R Medicine > RC Internal medicine > RC71-78.7 Examination. Diagnosis. Including radiography R Medicine > RC Internal medicine > RC952-954.6 Geriatrics |
Divisions: | 04-Faculty of Medicine > 11702-Internal Medicine (Sp |
Depositing User: | dr Fadel Fikri Suharto |
Date Deposited: | 16 Jan 2025 04:42 |
Last Modified: | 16 Jan 2025 04:42 |
URI: | http://repository.unsri.ac.id/id/eprint/164775 |
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