OPTIMASI LOSION TABIR SURYA DENGAN VARIASI KONSENTRASI EKOENZIM DAN ASAM STEARAT SERTA UJI NILAI SPF SECARA IN VITRO

FEBRIANA, ADE and Miksusanti, Miksusanti and Wijaya, Dina Permata (2025) OPTIMASI LOSION TABIR SURYA DENGAN VARIASI KONSENTRASI EKOENZIM DAN ASAM STEARAT SERTA UJI NILAI SPF SECARA IN VITRO. Undergraduate thesis, Sriwijaya University.

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Abstract

Excessive UV exposure can damage the skin, making sunscreen essential for protection. One potential ingredient that can be utilized is eco-enzyme, as it contains bioactive compounds such as flavonoids and phenolics, which exhibit UV protection activity. This study used eco-enzyme derived from the fermentation of pineapple peels, banana peels, and potato peels for 90 days, resulting in a pH of 3.717±0.055 and total flavonoid and phenolic contents of 104.974 mgQE/L and 198.403 mgGAE/L, respectively. SPF testing of the eco-enzyme at concentrations ranging from 10% to 50% showed an increase in SPF values from 17.246±0.027 to 42.428±0.191. The eco-enzyme was then formulated into a sunscreen lotion with varying concentrations of eco-enzyme and stearic acid. Formula optimization using Design Expert® 13 with a factorial design resulted in an optimal formula containing 40% eco-enzyme and 11.066% stearic acid, with a viscosity of 5,571.880 cP, pH of 5.207, adhesion time of 16.877 seconds, spreadability of 54.833 mm, wash-off resistance of 15.533 mL, and an SPF of 15.086. Stability testing of the optimal formula indicated that the lotion remained physically stable, although a significant decrease in pH was observed based on a paired sample t-test. However, the pH after the cycling test remained within the physiological pH range of the skin. The formulated eco-enzyme-based sunscreen lotion demonstrated its potential as an effective sunscreen, providing SPF protection in the ultra-protection category. Keywords: eco-enzyme, lotion, optimization, sunscreen, SPF

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: Ekoenzim
Subjects: R Medicine > RS Pharmacy and materia medica > RS400-431 Pharmaceutical chemistry
Divisions: 08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User: Ade Febriana
Date Deposited: 21 Mar 2025 04:24
Last Modified: 21 Mar 2025 04:24
URI: http://repository.unsri.ac.id/id/eprint/169680

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