AKTIVITAS ANTIBAKTERI DAN ANTIBIOFILM OLEH EKSTRAK ETANOL DAUN SIMPUR AIR(DILLENIA SUFFRUTICOSA GRIFF. EX HOOK) TERHADAP BAKTERI STREPTOCOCCUS MUTANS ATCC 31987

AZIZAH, NURLAILA and Widjajanti, Hary (2025) AKTIVITAS ANTIBAKTERI DAN ANTIBIOFILM OLEH EKSTRAK ETANOL DAUN SIMPUR AIR(DILLENIA SUFFRUTICOSA GRIFF. EX HOOK) TERHADAP BAKTERI STREPTOCOCCUS MUTANS ATCC 31987. Undergraduate thesis, Sriwijaya University.

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Abstract

Penelitian ini bertujuan untuk mengevaluasi aktivitas antibakteri dan antibiofilm dari ekstrak etanol daun simpur air (Dillenia suffruticosa) terhadap bakteri Streptococcus mutans. Masalah kesehatan gigi di Indonesia masih didominasi oleh karies gigi, yang sebagian besar disebabkan oleh plak gigi dan pembentukan biofilm oleh bakteri Streptococcus mutans. Biofilm meningkatkan resistensi bakteri terhadap pengobatan, sehingga pendekatan alternatif berbasis herbal menjadi penting. Uji fitokimia Dillenia suffruticosa diketahui mengandung senyawa aktif seperti flavonoid, alkaloid, tanin, saponin, steroid dan terpenoid yang memiliki potensi antibakteri dan antibiofilm. Aktivitas antibakteri dengan variasi konsentrasi 5%, 10%, 15%, dan 20% mampu menghambat pertumbuhan bakteri S.mutans dengan zona hambat paling tinggi 16 mm. Ekstrak etanol daun simpur air dengan variasi konsentrasi memiliki aktivitas antibiofilm dengan efektivitas presentase degradasi biofilm paling tinggi sebesar 95,13%. Visualisasi menggunakan Scanning Electron Microscopy (SEM) menunjukkan biofilm yang diberi ekstrak etanol daun simpur air terlihat tampak berkurangnya matriks EPS yang terurai dan renggang.

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: Antibakteri, Antibiofilm, Streptococcus mutans, Dillenia suffruticosa
Subjects: Q Science > QR Microbiology > QR1-502 Microbiology
Divisions: 08-Faculty of Mathematics and Natural Science > 46201-Biology (S1)
Depositing User: NURLAILA AZIZAH
Date Deposited: 11 Jul 2025 02:57
Last Modified: 11 Jul 2025 02:57
URI: http://repository.unsri.ac.id/id/eprint/177753

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