AKURASI RASIO TRIGLISERID DAN HIGH DENSITY LIPOPROTEIN SEBAGAI MARKER PREDIABETES

ERJALIA, DELA and Liberty, Iche Andriyani and Septadina, Indri Seta (2019) AKURASI RASIO TRIGLISERID DAN HIGH DENSITY LIPOPROTEIN SEBAGAI MARKER PREDIABETES. Undergraduate thesis, Sriwijaya University.

	Text RAMA_11201_04011381621178_0007029001_0016098103_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (471kB) | Request a copy
	Text RAMA_11201_04011381621178_0007029001_0016098103_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (188kB) | Request a copy
	Text RAMA_11201_04011381621178_0007029001_0016098103_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (216kB) | Request a copy
	Text RAMA_11201_04011381621178_0007029001_0016098103_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (10kB) | Request a copy
	Text RAMA_11201_04011381621178_0007029001_0016098103_07_lamp.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (1MB) | Request a copy
	Text RAMA_11201_04011381621178_TURNITIN.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (12MB) | Request a copy
Preview	Text RAMA_11201_04011381621178_0007029001_0016098103_01_front_fer.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (2MB) | Preview
	Text RAMA_04011381621178.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (3MB) | Request a copy
	Text RAMA_04011381621178_0007029001_0016098103_06_ref.pdf - Bibliography Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (128kB) | Request a copy

Abstract

Introduction: Prediabetes is a condition when blood glucose levels increases from the normal range and below the diagnostic threshold of diabetes. Prediabetes has a high potential for progresiveness into DM type 2. Early diagnosis of prediabetes and diabetes helps on selecting of the exact intervention, so that it can decrease the incidence of complication. This research was conducted to assess the accuracy of the TG / HDL ratio as a marker of insulin resistance that is more efficient, applicable and affordable. The purpose of this study is to assess the sensitivity, specificity, AUC, cut of point, PPV, NPV, LR +, LR - from TG, HDL and TG / HDL ratio. Method: This study uses data from the Integrated Haj Computerization System in Health (SISKOHATKES 2018). The number of participants are 5,564 people who met the criteria inclusion. The obtained data is analyzed by using STATA version 15 and MedCal. The result of diagnostic test is presented in the form of table and curve form of each marker, namely TG, HDL, TG / HDL ratio and it is compared to find marker that have high diagnostic test values. Results: Diagnostic values of each prediabetes marker is TG level with value cut of point > 80, sensitivity 84.3%, specificity 24.5%, AUC 0.55, LR+ 1.12, LR- 0.64 , PPV 84%, NPV 90%. HDL level cut of point value ≤57, sensitivity 69.5%, specificity 33.5%, AUC 0.50, LR+ 1.04, LR- 0.91, PPV 85% and NPV 86 %. TG / HDL ratio cut of point value> 1.46, sensitivity 80.8%, specificity 25.4%, AUC 0.54, LR+ 1.08, LR- 0.75, PPV 84% and NPV 87%. Conclusion: Based on research that has been conducted on Indonesian pilgrims, it can be concluded that the TG / HDL ratio can be as a marker as a prediabetes screening method because it has a high level of accuracy with value of cut of point > 1.46, sensitivity 80.8%, specificity 25, 4%, P = 0,000 (significant), AUC 0.54, LR+ 1.08, LR- 0.75, PPV 84% and NPV 87%. Keywords: Prediabetes, Triglyceride Ratio and High Density Lipoprotein, Insulin Resistance Markers

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Prediabetes, Rasio Trigliserid dan High Density Lipoprotein, Marker Resistensi Insulin
Subjects:	R Medicine > RC Internal medicine > RC627.5-632 Metabolic diseases
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Users 4106 not found.
Date Deposited:	10 Jan 2020 04:41
Last Modified:	10 Jan 2020 04:41
URI:	http://repository.unsri.ac.id/id/eprint/23672

Actions (login required)

View Item