Elfita, Elfita and Muharni, Muharni and Latief, Madyawati and Darwati, Darwati and Widiyantoro, Ari and Supriyatna, Supriyatna and Bahti, Husein H. and Dachriyanus, Dachriyanus and Cos, Paul and Maes, Louis and Foubert, Kenne and Apers, Sandra and Pieters, Luc (2009) Antiplasmodial and other constituents from four Indonesian Garcinia spp. Phytochemistry, 70 (7). pp. 907-912. ISSN 0031-9422
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Abstract
Phytochemical investigations of four Garcinia spp. from Indonesia, i.e. Garcinia griffithii T. Anderson, Garcinia celebica L., Garcinia cornea L. and Garcinia cymosa K. Schum (Clusiaceae), have resulted in the isolation of a xanthone, 1,5-dihydroxy-3,6-dimethoxy-2,7-diprenylxanthone, 1,7-dihydroxyxanthone, isoxanthochymol, \ensuremathβ-sitosterol-3-O-b-D-glucoside and stigmasterol-3-O-\ensuremathβ-D-glucoside from the stem bark of G. griffithii; friedelin and 3\ensuremathβ-hydroxy-23-oxo-9,16-lanostadien-26-oic acid or garcihombronane D from leaves of G. celebica; 23-hydroxy-3-oxo-cycloart-24-en-26-oic acid and epicatechin from stem bark of G. cornea; (±)-morelloflavone, morelloflavone-7-O-b-D-glucoside or fukugiside, the triterpene 3\ensuremathβ-hydroxy-5-glutinen-28-oic acid and canophyllol from stem bark of G. cymosa. The xanthone and garcihombronane D displayed a selective activity against Plasmodium falciparum; isoxanthochymol and the triterpene b-hydroxy-5-glutinen-28-oic acid a broad but non-selective antiprotozoal activity.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > QD Chemistry > QD1-999 Chemistry |
| Divisions: | 08-Faculty of Mathematics and Natural Science > 47201-Chemistry (S1) |
| Depositing User: | Dr. Elfita, M.Si |
| Date Deposited: | 16 Jan 2020 06:32 |
| Last Modified: | 16 Jan 2020 06:32 |
| URI: | http://repository.unsri.ac.id/id/eprint/24249 |
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