KARAKTERISTIK PATCH YANG DIINKORPORASI DENGAN SERBUK FREEZE DRYING BAWANG PUTIH DAN SIFAT ANTIBAKTERINYA TERHADAP STREPTOCOCCUS MUTANS(S. MUTANS)

GUSTIRANI, ARMALINDA and Miksusanti, Miksusanti and Elfita, Elfita (2019) KARAKTERISTIK PATCH YANG DIINKORPORASI DENGAN SERBUK FREEZE DRYING BAWANG PUTIH DAN SIFAT ANTIBAKTERINYA TERHADAP STREPTOCOCCUS MUTANS(S. MUTANS). Undergraduate thesis, Sriwijaya University.

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Abstract

The aim of this research was to make patch and know characteristhics of patch when incoporated with freeze drying of garlic powder by variation of concentration. To determine antibacterial properties freeze drying of garlic powder the concentration was varied 4, 6, 8 , and 10 mg/mL and tasted on bacteria S. mutans uses dilution method. Minimum inhibitory concentration of S.mutans obtained are incorporated into the patch with increasing concentration freeze drying of garlic powder 8, 16, 24, and 32 mg/mL, 40 mg/mL and antibacterial activity was determined using the dilution method. Characteristics patches was carried out by determining physical properties in the form of weight uniformity and thickness patch, folding endurances, and swelling index. Freezee drying of garlic powder and patch with minimum inhibitory concentration characterization used GC-MS. The result showed physical properties of weight uniformity 23-56 mg and thickness patch 0,02-0,19 mm, folding endurances >300 folds, also good swelling index. The best minimum inhibitory concentration of the freeze drying of garlic powder at concentration 8 mg/mL that can inhibit bacteria to 99,72% and patch are incorporated with minimum inhibitory 98,64% at concentration 40 mg/mL. The caractrization by GC-MS freeze drying of garlic powder, contains antibacteria compounds such as diallyl disulphide, diallyl tetrasulfide and diallyl trisulfide. Antibacterial compounds in patches are not detected because patch dissolve and difficult to separated.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Serbuk freeze drying bawang putih, patch, S. mutans dan antibakteri
Subjects:	Q Science > QD Chemistry > QD415-436 Biochemistry
Divisions:	08-Faculty of Mathematics and Natural Science > 47201-Chemistry (S1)
Depositing User:	Users 1077 not found.
Date Deposited:	07 Aug 2019 08:10
Last Modified:	07 Aug 2019 08:10
URI:	http://repository.unsri.ac.id/id/eprint/2812

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