EFEKTIVITAS EKSTRAK BAWANG PUTIH (Allium sativum) TERHADAP BAKTERI E. coli SECARA In Vitro

KUSUMAH, RAEHAN and Kamaluddin, Muhammad Totong and Amalia, Ella (2021) EFEKTIVITAS EKSTRAK BAWANG PUTIH (Allium sativum) TERHADAP BAKTERI E. coli SECARA In Vitro. Undergraduate thesis, Sriwijaya University.

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Abstract

Background : Escherichia coli is a normal bacterial flora that can cause many diseases. With the increasing rate of resistance to antibiotics, there is a tendency to use traditional medicine as an alternative medicine. Garlic (Allium sativum) has long been known as a medicinal plant which is proven to contain antibacterial compounds. This study aims to determine the effectiveness of garlic extract against E. coli bacteria in vitro. Method : Experimental in vitro research in the form of Post-test Only Control Group Design. Extraction of garlic was carried out by maceration method using 95% ethanol as solvent which was then evaporated using a rotary evaporator. The garlic extract was tested for antibacterial activity using agar diffusion and dilution methods to determine the minimum inhibitory concentration (MIC), with ciprofloocacin as a positive control. Data were analyzed using SPSS version 26. Results : Garlic extract is divided into four concentrations, 200 mg / ml, 100 mg / ml, 50 mg / ml, and 25 mg / ml. The concentration of 200 mg / ml formed the largest inhibition zone diameter of 11.75 ± 0.75 mm with a minimum inhibitory concentration of 50 mg / ml. The results of data analysis showed that there were differences in the effectiveness of each concentration of garlic extract and ciprofloxacin. Conclusion : Ciprofloxacin has higher effectiveness than garlic extract. Key words : Extract, ethanol, garlic, Allium sativum, Escherichia coli, ciprofloxacin

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Extract, ethanol, garlic, Allium sativum, Escherichia coli, ciprofloxacin
Subjects:	R Medicine > RM Therapeutics. Pharmacology > RM265-267 Antibiotic therapy. Antibiotics
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Users 10079 not found.
Date Deposited:	20 Jan 2021 03:27
Last Modified:	20 Jan 2021 03:27
URI:	http://repository.unsri.ac.id/id/eprint/40601

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