HUBUNGAN TUMOR INFILTRATING LYMPHOCYTES (TILs) DENGAN KARAKTERISTIK KLINIKOPATOLOGI PASIEN MELANOMA MALIGNA DI RSUP DR. MOHAMMAD HOESIN PALEMBANG PERIODE 1 JANUARI 2016-31 DESEMBER 2019

HIDAYATI, NURUL and Purnamawati, Ika Kartika Edi Poedjo and Nurtjahyo, Awan (2021) HUBUNGAN TUMOR INFILTRATING LYMPHOCYTES (TILs) DENGAN KARAKTERISTIK KLINIKOPATOLOGI PASIEN MELANOMA MALIGNA DI RSUP DR. MOHAMMAD HOESIN PALEMBANG PERIODE 1 JANUARI 2016-31 DESEMBER 2019. Undergraduate thesis, Sriwijaya University.

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Abstract

Background: Malignant melanoma is a malignant tumor of melanocytes. The incidence of malignant melanoma has increased every year. In Indonesia, melanoma accounts for 7.9% of all skin malignancies. Tumor infiltrating lymphocytes (TILs) is a reflection of a good immune response against melanoma cells. It is known that TIL infiltrating provides a good prognosis. This study aims to determine the relationship between TIL and the clinicopathology of malignant melanoma patients at RSUP DR. Mohammad Hoesin Palembang. Methods: This type of research was an observational analytic study with a cross sectional design using HE preparations for malignant melanoma in the Department of Pathology Anatomy, RSUP DR. Mohammad Hoesin Palembang. Results: From 34 samples, it was found that malignant melanoma was found mostly at the age of 40-64 years (70,6%), dominated by women (58,8%), many of the samples had a history of work in the room (64,7%), is common in the lower extremities (47,1%) and the most common type is nodular melanoma (41,2%). The number of samples with high and low TILs is the same. There was no relationship between TIL and age (p = 1,000), there was no relationship between TIL and gender (p = 1,000), there was no relationship between TIL and work (p = 0,473), there was no relationship between TIL and tumor location (p = 0,247) and there was no relationship between TIL and histopathological type (p = 0,502) of malignant melanoma. Conclusion: TIL has no significant relationship with age, sex, occupation, tumor location and histopathological type of malignant melanoma. Key words: Malignant melanoma, TILs, clinicopathological characteristics, prognostic factors

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Melanoma maligna, TILs, karakteristik klinikopatologi, faktor prognostik
Subjects:	R Medicine > RB Pathology > RB24-33 Pathological anatomy and histology
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Users 10088 not found.
Date Deposited:	20 Jan 2021 04:18
Last Modified:	20 Jan 2021 04:18
URI:	http://repository.unsri.ac.id/id/eprint/40616

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