OPTIMASI ULTRASONIC-ASSISTED EXTRACTION (UAE) DAUN BANDOTAN (Ageratum conyzoides) MENGGUNAKAN DESAIN FAKTORIAL DENGAN PARAMETER KADAR FLAVONOID TOTAL DAN AKTIVITAS ANTIOKSIDAN

LESTARI, RAE RESTA and Fitrya, Fitrya and Solihah, Indah (2018) OPTIMASI ULTRASONIC-ASSISTED EXTRACTION (UAE) DAUN BANDOTAN (Ageratum conyzoides) MENGGUNAKAN DESAIN FAKTORIAL DENGAN PARAMETER KADAR FLAVONOID TOTAL DAN AKTIVITAS ANTIOKSIDAN. Undergraduate thesis, Sriwijaya University.

Preview	Text RAMA_48201_08061281419040_0010127203_0008038802_01_front_ref.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (1MB) | Preview
	Text RAMA_48201_08061281419040_0010127203_0008038802_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (359kB) | Request a copy
	Text RAMA_48201_08061281419040_0010127203_0008038802_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (314kB) | Request a copy
	Text RAMA_48201_08061281419040_0010127203_0008038802_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (657kB) | Request a copy
	Text RAMA_48201_08061281419040_0010127203_0008038802_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (9kB) | Request a copy
	Text RAMA_48201_08061281419040_0010127203_0008038802_06_ref.pdf - Bibliography Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (396kB) | Request a copy
	Text RAMA_48201_08061281419040_0010127203_0008038802_07_lamp.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (768kB) | Request a copy

Abstract

Ultrasonic-assisted extraction is an alternative extraction method for extracting natural compounds. Optimization of ultrasonic extraction bandotan leaf aims to determine the optimal solvent concentration and extraction time based on determination of total flavonoid content and IC50 antioxidant activity. The study was conducted by varying the solvent concentration (30, 70, 96%) and ultrasonic extraction time (20, 40, 80 min). Determination of the best extraction conditions is done using factorial design. Based on Design Expert 10® analysis, solvent concentration factor and ultrasonic extraction time have effect on total flavonoid content and antioxidant activity of bandotan leaf. The best ultrasonic exctraction condition are obtained at 70% ethanol concentration and 40 min extraction time selected based on the highest desirability value. Ultrasonic extraction using 70% ethanol for 40 minutes resulted 51.733 mg/g total flavonoid and 116.636 μg/mL IC50 antioxidant values.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	ultrasonic-assisted extraction (UAE), Ageratum conyzoides, flavonoid, IC50 antioxidant, factorial design
Subjects:	R Medicine > RS Pharmacy and materia medica > RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) R Medicine > RS Pharmacy and materia medica > RS400-431 Pharmaceutical chemistry
Divisions:	08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User:	Mrs Dies Meirita Sari
Date Deposited:	16 Aug 2019 06:41
Last Modified:	16 Aug 2019 06:41
URI:	http://repository.unsri.ac.id/id/eprint/4455

Actions (login required)

View Item