ISOLASI DAN UJI AKTIVITAS ANTIBAKTERI SENYAWA METABOLIT SEKUNDER DARI FRAKSI ETIL ASETAT KULIT BATANG SEMPRAWANG (Dillenia alata)

RAHMAN, SUCI MARZULIA and Muharni, Muharni and Yohandini, Heni (2021) ISOLASI DAN UJI AKTIVITAS ANTIBAKTERI SENYAWA METABOLIT SEKUNDER DARI FRAKSI ETIL ASETAT KULIT BATANG SEMPRAWANG (Dillenia alata). Undergraduate thesis, Sriwijaya University.

	Text RAMA_47201_08031281722025.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (2MB) | Request a copy
	Text RAMA_47201_08031281722025_TURNITIN.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (7MB) | Request a copy
Preview	Text RAMA_47201_08031281722025_0004036903_0015117007_01_front_ref.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (1MB) | Preview
	Text RAMA_47201_08031281722025_0004036903_0015117007_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (410kB) | Request a copy
	Text RAMA_47201_08031281722025_0004036903_0015117007_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (303kB) | Request a copy
	Text RAMA_47201_08031281722025_0004036903_0015117007_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (878kB) | Request a copy
	Text RAMA_47201_08031281722025_0004036903_0015117007_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (280kB) | Request a copy
	Text RAMA_47201_08031281722025_0004036903_0015117007_06_ref.pdf - Bibliography Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (279kB) | Request a copy
	Text RAMA_47201_08031281722025_0004036903_0015117007_07_lamp.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (669kB) | Request a copy

Abstract

Semprawang ( Dillenia alata ) is a plant of the Dillenia genus which is traditionally used for the treatment of diseases. The leaves of D. alata are used as a medicine for scabies. The scientific information of D. alata plant is very limited. The aims of research were to isolate and antibacterial activity test of secondary metabolite compounds from the ethyl acetate fraction of D. alata stem bark. The research was initiated by extraction using maceration method with solvents with increasing polarity. The separation and purification were carried out using the chromatography methods and the structure of the isolated compound was determined by analyzing the spectroscopic data including FT-IR, 1 H-NMR and 13 C-NMR and by comparing the spectroscopic data literatur. Antibacterial activity test was carried out using the disc diffusion method with Escerichia coli and Staphylococcus aureus as the test bacteria. The pure compound was a white crystals as much as 62 mg. Based on the analysis of spectroscopic data and comparing with the literatur, the isolate compound is triterpenoid group that is betulinic acid. The isolated compound showed antibacterial activity with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) at 120 g/mL.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Antibakteri, Dillenia alata, triterpenoid, asam betulinat
Subjects:	Q Science > QD Chemistry > QD241-441 Organic chemistry
Divisions:	08-Faculty of Mathematics and Natural Science > 47201-Chemistry (S1)
Depositing User:	Suci Marzulia Rahman
Date Deposited:	02 Jun 2021 06:53
Last Modified:	02 Jun 2021 06:53
URI:	http://repository.unsri.ac.id/id/eprint/47256

Actions (login required)

View Item