Indrajaya, Taufik (2019) The Correlation between Polymorphism of β Fibrinogen Gene -455 G/A and Serum Fibrinogen Level with The Severity of Coronary Artery Stenosis In Coronary Artery Disease Patient (Turnitin). Turnitin Universitas sriwijaya, Bangladesh Journal of Medical Science. (Unpublished)
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Abstract
Background: Now a days coronary artery disease (CAD) becomes major cause of death. One among7 deaths in America caused by CAD. CAD is an atherosclerosis process, which progresively develops into plaque that will lead to stenosis of coronary artery lumen. Several studies found that high serum fibrinogen level is an independent and significant to the severity of artery coronary stenosis. Serum fibrinogen level determined by genetic factor. Polymorphism of fibrinogen gene β -455 G/A seem plays an important role in plasma fibrinogen level. Although some studies showed a significant correlation between polymorphism and cardiovascular diseases, but some other studies report inversely. Aim. To evaluate the correlation between the polymorphism of fibrinogen gene β -455 G/A and serum fibrinogen level with the severity of artery coronary stenosis. Method: This is an analytic correlative study with prospective approach without comparison. Coronary angiography was performed in catheterization labor in the department of internal medicine, while DNA analysis and PCR done in the department of microbiology in General Hospital dr Muhammad Husin Palembang- Indonesioa, since July 2015 until Agustus 2016. Samples are CAD patient who undergo for coronary angiography and fulfield the criterias. The severity of stenosis in coronary artery determined by Gensini score. This study included 31 patient.
| Item Type: | Other |
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| Subjects: | #3 Repository of Lecturer Academic Credit Systems (TPAK) > Results of Ithenticate Plagiarism and Similarity Checker |
| Divisions: | 04-Faculty of Medicine > 11702-Internal Medicine (Sp |
| Depositing User: | Dr.dr. Taufik Indrajaya |
| Date Deposited: | 13 Jul 2021 07:17 |
| Last Modified: | 13 Jul 2021 07:19 |
| URI: | http://repository.unsri.ac.id/id/eprint/49617 |
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