Salni, Salni and Marisa, Hanifa and repi, lili arista (2019) Antioxidant Activities Bioactive Compound of Ethyl Acetate Extracts fromrose myrtle Leaves (Rhodomyrtus tomentosa (Ait.) Hassk.). IOP Conf. Series: Materials Science and Engineering 857, 1 (5). pp. 1-5.
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Abstract
One of the plants traditionally used as medicine is rose myrtle(Rhodomyrtus tomentosa(Ait.) Hassk.). Rose myrtlehas the potential as an antioxidant because it has secondary metabolites including flavonoids, phenols, terpenoids, tannins, saponins, and steroids. The purpose of this study was to determine the fraction that has antioxidant activity and obtain antioxidant compounds from ethyl acetate extract ofrose myrtleleaves. The research methods included extraction by Soxhletasi, fractionation by vacuum liquid chromatography, purification of compounds with gravity columns, and antioxidant activity test using the DPPH method. The results obtained 32% yield of ethyl acetate extract which was then followed by fractionation. The fractionation results obtained 13 fractions. The fractions that have antioxidant activity namely fractions 5-6, 7, and 8. The fraction was continued to purification and obtained by compound E.1, compound E.2 from the essential oil, and compound E3 allegedlyrhodomyrtone. The bioactivecompound determined by IC50value obtained that E1, E2 and E3 that have IC50 value of 218, 207 and 90 μg/mL, respectively. The bioactive compounds of ethyl acetate extract have strong antioxidant activity in E3 and very weak in E1 and E2compounds.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > QP Physiology > QP(901)-(981) Experimental pharmacology |
| Divisions: | 08-Faculty of Mathematics and Natural Science > 46201-Biology (S1) |
| Depositing User: | Salni Salni |
| Date Deposited: | 20 Sep 2021 05:17 |
| Last Modified: | 20 Sep 2021 05:17 |
| URI: | http://repository.unsri.ac.id/id/eprint/50114 |
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