Anwar, Chairil (2022) Plagiarism_Granulocyte Colony Stimulating Factor (G-CSF) Quantitative Analysis in Plasmodium Vivax-infected Malaria Patients Experiencing Thrombocytopenia. Fakultas Kedokteran Universitas Sriwijaya.
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Granulocyte Colony Stimulating Factor (G-CSF) Quantitative Analysis in Plasmodium Vivax-infected Malaria Patients Experiencing Thrombocytopenia (1).pdf Download (2MB) | Preview |
Abstract
Background:P. Vivax has been refered as pathological factor underlyingincreasing prevalences ofhaematological abnormality including anemia and thrombocytopenia. Through the day, exact mechanism of thrombocytopenia in malaria infection has yet come to a conclusion, several hypothesis are still in considered, phagocytosis and platelets aggregation remain the major disscussion topics. G-CSF, cytocine with elevated serum quantity in P. Vivax infections, were responsible in increasing phagoctytosis and conducting direct effect on platelets aggregation using adequate ADP. Increasing number of ADP in malaria cases were correlated with erythrocyte haemolitic, leading to increasing platelets aggregation. Although numerous hypothesis has been compelled, only a-few research publication has been made corresponding to G-CSF serum level on malaria P. Vivax infection and its correlations to thrombocytopenic events.The study is intended to analyzethe relations between G-CSF serum levels and parasite numbers towards platelets profile in infected malaria P. Vivax patients.Methods: Study design using Prospective analysis. Thirty six patients with single infection of Malaria Vivax in Puskesmas Sukamaju (Primary Heath Care Centre) and Puskesmas Kota Karang were assessed for G-CSF plasma levels, platelet counts, and MPV. Data analysis were conducted using Spearman correlation methods with SPSS.Results:Study results showing significant correlation between G-CSF serum levels towards Platelet conts (R = -0,397(p = 0,016)), without significant correlation between G-CSF and MPV value(p = 0,874)Conclusion:G-CSF serum levels were related with thrombocytopenia, with no correlation towards MPV
| Item Type: | Other |
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| Subjects: | #3 Repository of Lecturer Academic Credit Systems (TPAK) > Results of Ithenticate Plagiarism and Similarity Checker |
| Divisions: | 04-Faculty of Medicine > 11901-Doctor Profession (Profesi) |
| Depositing User: | Prof chairil anwar |
| Date Deposited: | 17 Jul 2022 15:29 |
| Last Modified: | 17 Jul 2022 15:29 |
| URI: | http://repository.unsri.ac.id/id/eprint/72695 |
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