RASIONALITAS PENGGUNAAN ANTIDIABETIKA ORAL (ADO) DAN KOMBINASINYA PADA PASIEN RAWAT INAP PENDERITA DIABETES MELITUS TIPE 2 DI RUMAH SAKIT A.K. GANI KOTAMADYA PALEMBANG

ARSYAF, RAHMADIAN FATHIR and Kamaluddin, M. T. and Theodorus, Theodorus (2012) RASIONALITAS PENGGUNAAN ANTIDIABETIKA ORAL (ADO) DAN KOMBINASINYA PADA PASIEN RAWAT INAP PENDERITA DIABETES MELITUS TIPE 2 DI RUMAH SAKIT A.K. GANI KOTAMADYA PALEMBANG. Undergraduate thesis, Sriwijaya University.

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Abstract

Background : Diabetes Mellitus type 2 is an uncontagious chronic disease which has many complications and the prevalence rises every year. Therefore, Oral Antidiabetic therapy given to DM type 2 patients should be indicated properly and rationally. This study aimed to know the rationality of Oral Antidiabetic uses to DM type 2 patients who were hospitalized In RS.A.K. Gani Palembang from Agustus 2010 until Juli 2011. Method : this statistic descriptive study of drug utilization was conducted in RS.A.K.Gani Palembang started from November until December 2011. Population of this study is medical record of DM type 2 patients who were hospitalized from Agustus 2010 until Juli 2011. The samples are 50 medical records which are fiilfilled in inclusion criteria. Result: From 50 medical records, the re are 35 female patients (70%) and 15 male patients (30%). The most patients are 61-70 years old (30%). Oral Antidiabetic uses which not combine is 76% and combine with other drugs is 24%. Oral Antidiabetic uses with paten drugs is 38,46% and with generic drugs is 61,54%). Oral Antidiabetic uses such as Sulfonilurea is 43,08% and Biguanide is 56,92%. The Frequency of Glimepiride uses once daily is 100%, Glibenclamide once daily is 100%, Gliklazid once daily is 77,78% and Metformin twice daily is 40,5%, third daily is 48,6%. Glimepiride were given 1 mg dose is 50% and 2 mg dose is 50%, Glibenclamide were given 5 mg dose is 100%,, Gliklazid were given 80 mg dose is 100%, Metformin were given 500 mg dose is 94,59%, 850 mg dose is 5,41%. Oral Antidiabetic uses which were given 14 days is 73,85%. Interaction of Oral Antidiabetic, at most addition is 41,54%o, potentiation is 41,15%, antagonistic is 13,46%, follow up obtain in 81,54%, There are no contraindication in 84,62%, over prescribing is 9,23%, incorrect prescribing is 18,46% and under prescribing is 6,15%. Conclusion: There are Oral Antidiabetic uses 's irrationality and need to be fixed so that become more rational and achieve ejfective therapy with minimal side effect.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Oral Antidiabetic, Drug Utilization Study
Subjects:	R Medicine > RC Internal medicine > RC627.5-632 Metabolic diseases
Divisions:	04-Faculty of Medicine > 11201-Medicine (S1)
Depositing User:	Mrs Furika Furika
Date Deposited:	09 Dec 2022 06:36
Last Modified:	09 Dec 2022 06:36
URI:	http://repository.unsri.ac.id/id/eprint/83537

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