Wahyudi, Budi Eko and Salni, Salni and Setiawan, Arum (2022) Antioxidant Activity of Tembesu (Fagraea fragrans Roxb.) Leaf. BIOVALENTIA: Biological Research Journal, 8 (2). pp. 96-102. ISSN 2477-1392
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05. Antioxidant Activity of Tembesu (Fagraea fragrans Roxb.) Leaf.pdf Download (2MB) | Preview |
Abstract
Herbal medicine is becoming a trend in curing several diseases especially degenerative because of the bad effects of synthetic drugs. Tembesu plant (Fagraea fragrans Roxb.) is traditionally used for degenerative diseases. This study aims to separate bioactive compounds (active fraction), pure isolate compounds from tembesu leaf, then observe antioxidant activity. The methods used are maceration extraction, liquid-liquid fractionation, purification of compounds by gravity chromatography column and antioxidant activity by scavenging DPPH radicals. The results showed that the active antioxidant fractions were n-hexane and ethyl acetate fractions. The results of purification of antioxidant compounds, obtained 6 isolates N1, N2, N4, N5, E8 and E11. Antioxidant activity (IC50) of pure isolates N1 (13.72 ppm), N2 (28.93 ppm), N4 (110.44 ppm), N5 (177.23 ppm), E8 (82.50 ppm) and E11 (12 ,86 ppm). The antioxidant compounds that have been isolated are terpenes (N1, N2, N4, E8), phenols (N5) and flavonoids (E11). This study concluded that tembesu leaf have antioxidant potential. Antioxidant bioactive compounds in tembesu leaf have the potential to be developed into standardized herbs and phytopharmaceuticals.
| Item Type: | Article |
|---|---|
| Additional Information: | Jurnal Nasional Terakreditasi Sinta 3 |
| Subjects: | Q Science > QL Zoology > QL951-991 Embryology Q Science > QP Physiology > QP(901)-(981) Experimental pharmacology |
| Divisions: | 08-Faculty of Mathematics and Natural Science > 46201-Biology (S1) |
| Depositing User: | Dr Arum Setiawan |
| Date Deposited: | 16 Dec 2022 14:36 |
| Last Modified: | 16 Dec 2022 14:36 |
| URI: | http://repository.unsri.ac.id/id/eprint/83614 |
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