FITRIANA, HUMAIRA and K., Trisnawaty and Chairani, Shanty (2023) AKTIVITAS ANTIJAMUR EKSTRAK N-HEKSANA KULIT DUKU (LANSIUM DOMESTICUM CORR.) TERHADAP CANDIDA ALBICANS SECARA IN VITRO. Undergraduate thesis, Sriwijaya University.
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Abstract
Background: High colonization of Candida albicans in mouth can increase the risk of oral candidiasis. Duku peel (Lansium domesticum Corr.) has potential as antifungal material due to its terpenoid and phenolic content which can be extracted with n-hexane as solvent. The pupose of this study is to determine the antifungal activity of n-hexane extract of duku peel against Candida albicans. Method: This study used laboratorium experimental with post test only control group study design. Antifungal activity was determined using disc diffusion method on five sample groups: n-hexane extract of duku peel 15%, 20%, and 25%, nystatin as positive control, and aquadest as negative control. Antifungal activity was determined by measuring clear zone around the disc and measured with caliper in millimeter. The measurement of inhibition zone was analyzed with One Way ANOVA test. Result: There were no inhibition zone on n-hexane extract of duku peel with concentration of 15%, 20%, 25% and negative control while positive control had average inhibition zone diameter of 11,85 mm. Conclusion: N-hexane extract of duku peel with concentration of 15%, 20%, and 25% did not have antifungal activity against Candida albicans.
Item Type: | Thesis (Undergraduate) |
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Uncontrolled Keywords: | antifungal, Candida albicans, Lansium domesticum |
Subjects: | R Medicine > RK Dentistry > RK1-715 Dentistry |
Divisions: | 04-Faculty of Medicine > 12201-Dentistry (S1) |
Depositing User: | Humaira Fitriana |
Date Deposited: | 06 Feb 2023 02:09 |
Last Modified: | 06 Feb 2023 02:09 |
URI: | http://repository.unsri.ac.id/id/eprint/89071 |
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