PENGARUH PEMBERIAN EKSTRAK ETANOL KULIT BUAH PETAI (PARKIA SPECIOSA HASSK.) TERHADAP DAYA INGAT MENCIT JANTAN PUTIH (MUS MUSCULUS) GALUR SWISS-WEBSTER

DESYTA, MIRZA and Herlina, Herlina and Novita, Rennie Puspa (2019) PENGARUH PEMBERIAN EKSTRAK ETANOL KULIT BUAH PETAI (PARKIA SPECIOSA HASSK.) TERHADAP DAYA INGAT MENCIT JANTAN PUTIH (MUS MUSCULUS) GALUR SWISS-WEBSTER. Undergraduate thesis, Sriwijaya University.

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Abstract

A study have been done to investigate the effect of rind petai ethanolic (Parkia speciosa Hassk.) on memory enhancement of white male mice of Swiss-Webster strain which inhibited with scopolamine using passive avoidance test method. The experimental study used 30 mice divided into 6 groups, which were untreated normal group, positive control group given 500 mg/kgBW piracetam, negative control group given 1% sodium CMC suspension, and treatment group 1, treatment 2, treatment 3 were each given ethanol extract of rind petai with dose of 75, 150, and 300 mg/kgBW orally for 21 days. Retention duration data obtained was analyzed by one-way ANOVA and continued with LSD test with 95% confidence level. Ethanol extract of rind petai contain flavonoid as much 27,6 mg. The results showed that ethanol extract of rind petai dose 75, 150, and 300 mg/kgBW has no significant difference (p>0.05) with positive control group but is difference (p<0.05) with negative control group and normal control group. Based on the result of the research, it can be concluded that ethanol extract of rind petai 75, 150, and 300 mg/kgBW give effect to improve the memory of mice induced by scopolamine, with dose 300 mg/kgBW show best effect because has the longest retention duration.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	rind petai, memory enhancement, passive avoidance test
Subjects:	R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions:	08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User:	Administrator Library
Date Deposited:	31 Jul 2019 05:04
Last Modified:	02 Aug 2019 06:59
URI:	http://repository.unsri.ac.id/id/eprint/1378

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