EFEK PEMBERIAN SNACK BAR EKSTRAK DAUN PEGAGAN (Centella asiatica L.) KOMBINASI DAUN GAMBIR (Uncaria gambir Roxb.) TERHADAP FUNGSI KOGNITIF PADA TIKUS PUTIH

HUZZULAM, MIFTAH MISHBAH and Shiyan, Shaum and Solihah, Indah (2023) EFEK PEMBERIAN SNACK BAR EKSTRAK DAUN PEGAGAN (Centella asiatica L.) KOMBINASI DAUN GAMBIR (Uncaria gambir Roxb.) TERHADAP FUNGSI KOGNITIF PADA TIKUS PUTIH. Undergraduate thesis, Sriwijaya University.

	Text RAMA_48201_08061381823094.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (3MB) | Request a copy
	Text RAMA_48201_08061381823094_TURNITIN.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (5MB) | Request a copy
Preview	Text RAMA_48201_08061381823094_0028058601_0008038802_01_front_ref.pdf - Accepted Version Available under License Creative Commons Public Domain Dedication. Download (1MB) | Preview
	Text RAMA_48201_08061381823094_0028058601_0008038802_02.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (498kB) | Request a copy
	Text RAMA_48201_08061381823094_0028058601_0008038802_03.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (819kB) | Request a copy
	Text RAMA_48201_08061381823094_0028058601_0008038802_04.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (796kB) | Request a copy
	Text RAMA_48201_08061381823094_0028058601_0008038802_05.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (217kB) | Request a copy
	Text RAMA_48201_08061381823094_0028058601_0008038802_06_ref.pdf - Bibliography Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (462kB) | Request a copy
	Text RAMA_48201_08061381823094_0028058601_0008038802_07_lamp.pdf - Accepted Version Restricted to Repository staff only Available under License Creative Commons Public Domain Dedication. Download (2MB) | Request a copy

Abstract

Gotu Kola (Centella asiatica L.) and gambier (Uncaria gambir Roxb.) is a plant that is believed to have many benefits. The high antioxidant content, especially flavonoids, triterpenoids, polyphenols, saponins from gotu kola and gambier leaves are believed to improve memory. This study aims to determine the levels of flavonoids, levels of proximate snack bar characteristics , and to determine the error score on the effect of giving several treatment groups to improve memory by using the Eight Arm RAM. The test animals used were male wistar rats aged 2-4 months. The test animals were divided into 5 groups consisting of the normal group given aquadest, the positive group was given pyracetam 500 mg/kgBW, the treatment group I was given gotu kola simplicia 300 mg/kgBW a combination of gambier leaves simplicia 200 mg/kgBW, the second treatment group was given 300 mg gotu kola extract/kgBW combination of gambier leaves extract 200 mg/kgBW, and treatment group III was given a snack bar. The total flavonoid content in the gotu kola extract and gambier leaf were 32.58 mgQE/g and 19,88 mgQE/g, respectively. The proximate characteristics of the snack bar obtained water content of 8,42%, ash content of 1,43%, protein content of 7,64%, fat content of 20,44%, carbohydrate content of 62,05%, and calorie content of 250,13%. The result of the error scores obtaines were analyzed with One Way Anova and continued with Duncan’s test. Measurement of memory activity in the pre test and post test showed a significant difference in each treatment (P>0,05). Measurement of memory activity also used the Paired T-test, resulting in the pre test and post test in each treatment group showed a difference significant (P<0,05). Based on the results of the study it can be concluded that the best treatment groups were shown by treatment groups II and III. Keywords: Gotu kola, Gambier, Snack bar, RAM, Memory

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Pegagan, Gambir, Snack bar, RAM, Daya ingat
Subjects:	R Medicine > RS Pharmacy and materia medica > RS160-167 Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
Divisions:	08-Faculty of Mathematics and Natural Science > 48201-Pharmacy (S1)
Depositing User:	Miftah Mishbah Huzzulam
Date Deposited:	01 Feb 2023 03:27
Last Modified:	01 Feb 2023 03:27
URI:	http://repository.unsri.ac.id/id/eprint/88798

Actions (login required)

View Item